L. Ziganshina

Publications95
h-index12
Citations718
Highly Influential Citations47
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Effects of extracellular pH on agonism and antagonism at a recombinant P2X2 receptor
Under voltage‐clamp conditions, the activity of agonists and antagonists at a recombinant P2X2 receptor expressed in Xenopus oocytes was examined at different levels of extracellular pH (pHe). In… Expand
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Full sensitivity of P2times2 purinoceptor to ATP revealed by changing extracellular pH
A full pharmacological characterization was carried out on a recombinant ATP‐gated ion channel (P2times2 purinoceptor) expressed in Xenopus oocytes. This slowly‐desensitizing neuronal P2times2… Expand
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Characteristics of ecto-ATPase of Xenopus oocytes and the inhibitory actions of suramin on ATP breakdown
Ecto-ATPase activity of Xenopus oocytes was studied by measuring the production of inorganic phosphate (Pi) from the breakdown of extracellular ATP. Enzyme activity involved Ca2+/Mg2+-dependent and… Expand
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A novel P1 purinoceptor activates an outward K+ current in follicular oocytes of Xenopus laevis.
Follicular oocytes of Xenopus laevis possess P1 purinoceptors where, seemingly, both adenosine (Ado) and ATP are agonists. The basis of ATP agonism at this P1 purinoceptor was investigated using… Expand
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Academic medicine in Russia.
Academic medicine, along with professionalism of the medical community in Russia underwent a remarkable evolution from the Revolution through the decline of the Soviet Union. The Soviet period… Expand
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Effects of P2-purinoceptor antagonists on degradation of adenine nucleotides by ecto-nucleotidases in folliculated oocytes of Xenopus laevis.
The aim of the present study was to examine the effects of a number of P2-purinoceptor antagonists on degradation of adenine nucleotides by Xenopus laevis oocyte ecto-nucleotidase. Folliculated… Expand
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Effects of divalent cations and La3+ on contractility and ecto‐ATPase activity in the guinea‐pig urinary bladder
1 Several cations (Ba2+, Cd2+, Co2+, Cu2+, Mn2+, Ni2+, Zn2+ and La3+, all as chloride salts, 1–1000 μm) were tested in the guinea‐pig urinary bladder for their ability to: (i) modify contractile… Expand
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Effects of P2-purinoceptor antagonists on ecto-nucleotidase activity of guinea-pig vas deferens cultured smooth muscle cells.
Ecto-nucleotidase activity was studied on primary cultures of guinea-pig vas deferens smooth muscle cells by measuring the inorganic phosphate (Pi) production using ATP as a substrate. The… Expand
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Temperature dependency of P2 receptor-mediated responses.
The P2 receptor-mediated responses of isolated guinea pig urinary bladder and vas deferens (P2X receptors) and taenia caeci (P2Y receptors) were registered at the three temperature conditions of 30,… Expand
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Effects of alpha,beta-unsaturated sulphones and phosphonium salts on ecto-ATPase activity and contractile responses mediated via P2 chi-purinoceptors.
1. In the guinea-pig urinary bladder and vas deferens, several alpha,beta-unsaturated sulphones and phosphonium salts that were tested inhibited ecto-ATPase activity. The sulphones were more active… Expand
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