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Saccharomyces boulardii Administration Changes Gut Microbiota and Attenuates D-Galactosamine-Induced Liver Injury
Growing evidence has shown that gut microbiome is a key factor involved in liver health. Therefore, gut microbiota modulation with probiotic bacteria, such as Saccharomyces boulardii, constitutes aExpand
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Focal Adhesion Kinase Regulates Hepatic Stellate Cell Activation and Liver Fibrosis
Understanding the underlying molecular mechanisms of liver fibrosis is important to develop effective therapy. Herein, we show that focal-adhesion-kinse (FAK) plays a key role in promoting hepaticExpand
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Impact of HLA-B*58:01 allele and allopurinol-induced cutaneous adverse drug reactions: evidence from 21 pharmacogenetic studies
Allopurinol is widely used for hyperuricemia and gouty arthritis, but is associated with cutaneous adverse drug reactions (CADRs). Recently, HLA-B*58:01 allele was identified as a strong geneticExpand
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Quantitative assessment of common genetic variations in HLA-DP with hepatitis B virus infection, clearance and hepatocellular carcinoma development
Hepatitis B virus (HBV) infection is the predominant risk factor for chronic hepatitis B (CHB), liver cirrhosis (LC) and hepatocellular carcinoma (HCC). Recently, genome-wide association studies haveExpand
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TNF‐&agr; increases Staphylococcus aureus‐induced death of human alveolar epithelial cell line A549 associated with RIP3‐mediated necroptosis
Aim: To explore the role of tumor necrosis factor‐alpha (TNF‐&agr;) on Staphylococcus aureus‐induced necroptosis in alveolar epithelial cells. Main methods: The A549 alveolar epithelial cell line wasExpand
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Limonoids and triterpenoid from fruit of Swietenia macrophylla.
Five new limonoids, swieteliacates A-E (1-5) and a tirucallane-type triterpenoid, swietesenin (6), together with four known compounds (7-10) were isolated from fruit of Swietenia macrophylla. TheirExpand
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Carboplatin-induced hematotoxicity among patients with non-small cell lung cancer: Analysis on clinical adverse events and drug-gene interactions
In order to clarify the risk of hematotoxicity of carboplatin, we inspected 19901 case reports of non-small cell lung cancer patients that were submitted to the FDA Adverse Event Reporting SystemExpand
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A multi-channel watermarking scheme based on HVS and DCT-DWT
With the rapid growth of the Internet and multimedia processing techniques, digital data becomes much easier to obtain which brings the problem of copyright protection. Among various ways, digitalExpand
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In Vitro Human Dihydroorotate Dehydrogenase Inhibitory, Anti-inflammatory and Cytotoxic Activities of Alkaloids from the Seeds of Nigella glandulifera.
Four new dolabellane-type diterpene alkaloids, glandulamines A - D (1:  - 4: ), together with twelve known compounds (5:  - 16: ), were isolated from the seeds of Nigella glandulifera using repeatedExpand
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The Generalized Broer-Kaup-Kupershmidt System and its Hamiltonian Extension
Abstract The generalized Broer-Kaup-Kupershmidt (generalized BKK) isospectral problem, including the x-derivative of potential, is considered based on Lie algebra A1. The variational trace identityExpand
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