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Genetic variants of CYP2D6 gene and cancer risk: a HuGE systematic review and meta-analysis.
OBJECTIVE Genetic polymorphisms in metabolic enzymes are associated with numerous cancers. A large number of single nucleotide polymorphisms (SNPs) in the CYP2D6 gene have been reported to associateExpand
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  • Open Access
A High-Saturated-Fat, High-Sucrose Diet Aggravates Bone Loss in Ovariectomized Female Rats.
BACKGROUND Estrogen deficiency in women and high-saturated fat, high-sucrose (HFS) diets have both been recognized as risk factors for metabolic syndrome. Studies on the combined actions of these 2Expand
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  • Open Access
Vascular endothelial growth factor gene polymorphisms and colorectal cancer risk: a meta-analysis.
Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen involved in a number of pathologic processes, including angiogenesis, tumor growth and metastasis. Polymorphisms ofExpand
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8-Prenylgenistein, a prenylated genistein derivative, exerted tissue selective osteoprotective effects in ovariectomized mice
Our previous study reported that the in vitro osteogenic effects of 8-prenylgenistein (8PG) were more potent than its parent compound genistein. This study aimed to evaluate the osteoprotectiveExpand
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  • Open Access
[Correlation between the function of monocytes/macrophages and disease progression in people living with HIV/AIDS in several provinces in China].
OBJECTIVE To investigate the functional states of peripheral blood monocytes/macrophages and their relation with the disease progression in people living with HIV/AIDS (PWHA). METHODS PeripheralExpand
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Optically stimulated luminescence dating of cave deposits at the Xiaogushan prehistoric site, northeastern China.
The Xiaogushan cave site is one of the most important prehistoric sites in North China. The stone and bone artifacts found in the cave are similar to European contemporaneous artifacts. Cave depositsExpand
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Functional polymorphisms in the interleukin-12 gene contribute to cancer risk: evidence from a meta-analysis of 18 case-control studies.
BACKGROUND Emerging evidence from preclinical and clinical studies has shown that interleukin-12 (IL-12) has some effectiveness against endogenously arising carcinogenesis. Several potentiallyExpand
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Association of functional polymorphisms of the XRCC4 gene with the risk of breast cancer: a meta-analysis.
OBJECTIVE X-ray cross-complementing group 4 (XRCC4) is a major repair gene for DNA double-strand breaks (DSB) in the non-homologous end-joining (NHEJ) pathway. Several potentially functionalExpand
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Ethanol Extract of Fructus ligustri lucidi Increased Circulating 1,25(OH)2D3 Levels, but Did Not Improve Calcium Balance in Mature Ovariectomized Rats.
Our previous studies found that different extracts or fractions of Fructus ligustri lucidi (FLL) played different roles in altering the regulation of bone and mineral metabolism in different animalExpand
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Genetic Variants of CYP 2 D 6 Gene and Cancer Risk : A HuGE Systematic Review and Meta-analysis
Cytochrome P450 (CYP450) is a large and diverse group of metabolic enzymes containing heme, consisted by many isozyme, also known as P450 gene superfamily (Wexler et al., 2004). CYP450 is mainly inExpand
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  • Open Access