L. Zheng

Publications45
h-index8
Citations799
Highly Influential Citations37
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Molecular Cloning and Functional Analysis of Polyphosphoinositide-dependent Phospholipase D, PLDβ, from Arabidopsis*
A novel plant phospholipase D (PLD; EC 3.1.4.4) activity, which is dependent on phosphatidylinositol 4,5-bisphosphate (PIP2) and nanomolar concentrations of calcium, has been identified in… Expand
  • 104
  • 12
The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer’s disease
Mitochondria play critical roles in neuronal function and almost all aspects of mitochondrial function are altered in Alzheimer neurons. Emerging evidence shows that mitochondria are dynamic… Expand
  • 210
  • 11
Abnormal mitochondrial dynamics and neurodegenerative diseases.
Mitochondrial dysfunction is a prominent feature of various neurodegenerative diseases. A deeper understanding of the remarkably dynamic nature of mitochondria, characterized by a delicate balance of… Expand
  • 210
  • 3
Inhibiting toxic aggregation of amyloidogenic proteins: a therapeutic strategy for protein misfolding diseases.
BACKGROUND The deposition of self-assembled amyloidogenic proteins is associated with multiple diseases, including Alzheimer's disease, Parkinson's disease and type 2 diabetes mellitus. The toxic… Expand
  • 168
  • 3
Salvation of the fallen angel: Reactivating mutant p53
The transcription factor p53 is known as the guardian of the genome for its powerful anti‐tumour capacity. However, mutations of p53 that undermine their protein structure, resulting in loss of… Expand
  • 13
  • 2
Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1.
Hepatic insulin sensitivity is critical for glucose homeostasis, and insulin resistance is a fundamental syndrome found in various metabolic disorders, including obesity and type 2 diabetes. Despite… Expand
  • 11
  • 1
Disruption of OsEXO70A1 Causes Irregular Vascular Bundles and Perturbs Mineral Nutrient Assimilation in Rice
  • Bin Tu, L. Hu, +10 authors S. Li
  • Biology, Medicine
  • Scientific reports
  • 22 December 2015
Normal uptake, transportation, and assimilation of primary nutrients are essential to plant growth. Tracheary elements (TEs) are tissues responsible for the transport of water and minerals and… Expand
  • 13
  • 1
Unique Epitope of Bovine Immunodeficiency Virus Gag Protein Spans the Cleavage Site between p16MA and p2L
ABSTRACT Bovine immunodeficiency virus (BIV) and Jembrana disease virus (JDV) are closely related bovine lentiviruses that are difficult to distinguish by presently available diagnostic methods.… Expand
  • 9
  • 1
Biochar mediates microbial communities and their metabolic characteristics under continuous monoculture.
Biochar amendment has been extensively used to improve plant performance and suppress disease in monoculture systems; however, few studies have focused on the underlying control mechanisms of… Expand
  • 3
  • 1
[Pedigree investigation and genetic analysis of a case with p blood group].
  • Y. Liu, L. Zheng, +4 authors J. Sun
  • Biology, Medicine
  • Zhonghua yi xue yi chuan xue za zhi = Zhonghua…
  • 1 December 2013
OBJECTIVE To explore the molecule basis of a p blood group in a patient with gastric carcinoma. METHODS The p phenotype was determined with serological method. Inheritance of the p phenotype was… Expand
  • 2
  • 1