• Publications
  • Influence
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
TLDR
Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection. Expand
Relationship between the ABO Blood Group and the COVID-19 Susceptibility
TLDR
Comparison of the ABO blood group distribution with COVID-19 confirmed by SARS-CoV-2 test from three hospitals in Wuhan and Shenzhen, China with that in normal people from the corresponding regions showed that blood group A was associated with a higher risk for acquiring CO VID-19 compared with non-A blood groups, whereas blood group O wasassociated with a lower risk for the infection compared withNon-O blood groups. Expand
Utility of a physiologically–based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug–drug–disease interaction scenario for rivaroxaban during the drug review process:
TLDR
The primary objective of this communication was to quantitatively predict changes in rivaroxaban exposure when individuals with varying degrees of renal impairment are co‐administered with another drug that is both a P‐gp and a moderate CYP3A4 inhibitor. Expand
Phase IB Study of PKC412, an Oral FLT3 Kinase Inhibitor, in Sequential and Simultaneous Combinations with Daunorubicin and Cytarabine (DA) Induction and High-Dose Cytarabine Consolidation in Newly
TLDR
PKC412 at 50 mg po bid can be given safely and tolerably in newly diagnosed ≤ 60 years old AML patients in combination with DA and high dose cytarabine in a phase Ib trial. Expand
Dietary interventions for mineral and bone disorder in people with chronic kidney disease.
TLDR
There was limited and low-quality evidence to indicate that calcium-enriched bread increased serum calcium and calcium × phosphate product and there was insufficient reporting of design and methodological aspects among the included studies to enable robust assessment of risk of bias. Expand
The Influence of Body Size Descriptors on the Estimation of Kidney Function in Normal Weight, Overweight, Obese, and Morbidly Obese Adults
TLDR
No kidney function equation was consistently accurate and unbiased across weight, mCrCI, and estimate ranges. Expand
Risk factors of stroke-associated pneumonia in Chinese patients
TLDR
SAP was more closely related with diabetes, age, consciousness, days of hospitalization, tracheal intubation,tracheal incision, nasal feeding treatment, and the application of H2-receptor blocking agents and antimicrobials. Expand
A randomised, multicentre open-label phase II study to evaluate the efficacy, tolerability and pharmacokinetics of oral vinorelbine plus cisplatin versus intravenous vinorelbine plus cisplatin in
TLDR
Oral VRL could be an effective alternative to intravenous VRL as a first-line treatment for NSCLC, as it optimises treatment convenience while maintaining high efficacy. Expand
Relationship between the ABO Blood Group and the COVID-19 Susceptibility
TLDR
It was found that blood group A was associated with an increased risk of infection, whereas group O wasassociated with a decreased risk. Expand
...
1
2
3
4
5
...