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Development of transgenic Artemisia annua (Chinese wormwood) plants with an enhanced content of artemisinin, an effective anti‐malarial drug, by hairpin‐RNA‐mediated gene silencing
- L. Zhang, Fuyuan Jing, +5 authors Kexuan Tang
- Medicine, Biology
- Biotechnology and applied biochemistry
- 1 March 2009
Artemisinin is an effective anti‐malarial drug isolated from Artemisia annua L. (Chinese wormwood), but the content of artemisinin in A. annua is low. In the present study we explored the possibility… Expand
Risk factors for neck nodal metastasis in papillary thyroid microcarcinoma: a study of 1066 patients.
CONTEXT The surgical management of papillary thyroid microcarcinoma (PTMC), especially regarding the necessity of central lymph node dissection, remains controversial. OBJECTIVE The objective of… Expand
Epigenetic activation of the MiR-200 family contributes to H19-mediated metastasis suppression in hepatocellular carcinoma.
Although numerous long non-coding RNAs (lncRNAs) have been identified in mammals, many of their biological roles remain to be characterized. Early reports suggest that H19 contributes to… Expand
Bile Acids and Dysbiosis in Non-Alcoholic Fatty Liver Disease
BACKGROUND & AIMS Non-alcoholic fatty liver disease (NAFLD) is characterized by dysbiosis. The bidirectional effects between intestinal microbiota (IM) and bile acids (BA) suggest that dysbiosis may… Expand
The prevalence of mild cognitive impairment about elderly population in China: a meta‐analysis
- Hongwei Nie, Y. Xu, +5 authors Y. Wu
- International journal of geriatric psychiatry
- 1 June 2011
Dementia has been a major public health problem and mild cognitive impairment is considered the pre‐dementia syndrome in recent years. However, there has not yet been a systematic analysis of the… Expand
Irisin improves endothelial function in type 2 diabetes through reducing oxidative/nitrative stresses.
- D. Zhu, Haichang Wang, +10 authors L. Tao
- Journal of molecular and cellular cardiology
- 1 October 2015
Vascular complications are the major causes of death in patients with diabetes, and endothelial dysfunction is the earliest event in vascular complications of diabetes. It has been reported that… Expand
Ethanol-wet bonding technique may enhance the bonding performance of contemporary etch-and-rinse dental adhesives.
- F. Li, Xiao-Yang Liu, L. Zhang, Jun-jun Kang, Ji-hua Chen
- Medicine, Materials Science
- The journal of adhesive dentistry
- 1 April 2012
PURPOSE To determine whether bonds of contemporary etch-and-rinse adhesives made with ethanol-wet bonding are stronger and more durable than those made with water-wet bonding, and to explore the… Expand
Effects of long-term low-dose cadmium exposure on genomic DNA methylation in human embryo lung fibroblast cells.
Cadmium is a toxic transition metal of continuing occupational and environmental concern. As a well-recognized human carcinogen, its carcinogenic mechanisms are still poorly understood. Cadmium has… Expand
Beneficial effect of galanin on insulin sensitivity in muscle of type 2 diabetic rats
The aim of this study was to determine whether enhanced galanin (GAL) release induced by exercise would elevate insulin sensitivity and glucose transporter 4 (GLUT4) concentration in the plasma… Expand
Loss of Cartilage Structure, Stiffness, and Frictional Properties in Mice Lacking PRG4
Objective To assess the role of the glycoprotein PRG4 in joint lubrication and chondroprotection by measuring friction, stiffness, surface topography, and subsurface histology of the hip joints of… Expand