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  • W. Shu, H. Yang, L. Zhang, M. Lu, E. Morrisey
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 2001 (First Publication: 20 July 2001)
  • Epithelial gene expression in the lung is thought to be regulated by the coordinate activity of several different families of transcription factors including the Fox family of winged-helix/forkheadExpand
  • J. Goodier, L. Zhang, M. Vetter, H. Kazazian
  • Medicine, Biology
  • Molecular and Cellular Biology
  • 2007 (First Publication: 11 June 2007)
  • ABSTRACT LINE-1 retrotransposons constitute one-fifth of human DNA and have helped shape our genome. A full-length L1 encodes a 40-kDa RNA-binding protein (ORF1p) and a 150-kDa protein (ORF2p) withExpand
  • Gwendolyn T. Wong, D. Manfra, +10 authors E. Parker
  • Biology
  • Journal of Biological Chemistry
  • 2004 (First Publication: 26 March 2004)
  • Inhibition of γ-secretase, one of the enzymes responsible for the cleavage of the amyloid precursor protein (APP) to produce the pathogenic β-amyloid (Aβ) peptides, is an attractive approach to theExpand
  • L. Zhang, Xiaoyu Pan, J. Hershey
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2007 (First Publication: 23 February 2007)
  • Transcriptional and post-transcriptional regulatory mechanisms are commonly accepted paradigms of tumorigenesis. The view is emerging that deregulation of translation contributes importantly toExpand
  • Xiaoming Hu, Zhongfang Weng, +8 authors J. Chen
  • Biology, Medicine
  • The Journal of Neuroscience
  • 2011 (First Publication: 5 January 2011)
  • The peroxiredoxin (PRX) family of antioxidant enzymes helps maintain the intracellular reducing milieu and suppresses apoptosis in non-neuronal cells. However, whether PRX can inhibit neuronalExpand