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Evidence that selective changes in the lipid composition of raft-membranes occur during respiratory syncytial virus infection.
We examined the structure of lipid-raft membranes in respiratory syncytial virus infected cells. Cholesterol depletion studies using methyl-beta-cyclodextrin suggested that membrane cholesterol wasExpand
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ALDH2 protects against stroke by clearing 4-HNE
Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme that metabolizes ethanol and toxic aldehydes such as 4-hydroxy-2-nonenal (4-HNE). Using an unbiased proteomic search, we identified ALDH2Expand
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Aquaporin 1 expression in the testis, epididymis and vas deferens of postnatal ICR mice
Aquaporin 1 (AQP1) is one of the water channels involved in water transfer and reabsorption. The results of a reverse transcription‐polymerase chain reaction (RT‐PCR) indicated that the level of AQP1Expand
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The phosphoinositide 3-kinase/Akt-signal pathway mediates proliferation and secretory function of hepatic sinusoidal endothelial cells in rats after partial hepatectomy.
OBJECTIVE To investigate the role of AKT signaling pathway in hepatic sinusoidal endothelial cells (SECs) early after partial hepatectomy in rats and the regulatory mechanisms involved. METHODS TheExpand
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Sanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation
  • L. Ying, G. Li, +12 authors Y. Wang
  • Chemistry, Medicine
  • Acta Pharmacologica Sinica
  • 1 February 2015
Aim:Small GTPase Rac1 is a member of the Ras superfamily, which plays important roles in regulation of cytoskeleton reorganization, cell growth, proliferation, migration, etc. The aim of this studyExpand
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An injectable conductive Gelatin-PANI hydrogel system serves as a promising carrier to deliver BMSCs for Parkinson's disease treatment.
  • Jinhua Xue, Y. Liu, +8 authors L. Zhang
  • Materials Science, Medicine
  • Materials science & engineering. C, Materials for…
  • 1 July 2019
Parkinson's disease (PD) is a long-term neurodegenerative disorders that characterized by a progressive loss of dopaminergic neurons in substantia nigra pars compacta (SNc). Bone marrow stromal cellsExpand
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Construction of HBV targeted ribonuclease and its expression in 2.2.15 cell line
Aim To construct human eosinophil derived neurotoxin(hEDN) and HBV core protein(HBVc)eukaryotic fusion expression vector, which will be used to inhibit HBV replication. Methods The total RNA wereExpand
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Different roles of Rac1 in the acquisition and extinction of methamphetamine-associated contextual memory in the nucleus accumbens
Rationale: Repeated methamphetamine (METH) exposure induces long-term cognitive deficits and pathological drug-associated memory that can be disrupted by manipulating memory reconsolidation andExpand
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Detection of disseminated tumor cells in the peripheral blood of patients with laryngeal or laryngopharyngeal carcinomas
OBJECTIVE To investigate the diagnostic and prognostic value of molecular biological detection of DTC in peripheral blood. METHODS 32 cases of laryngeal or laryngopharyngeal carcinoma wereExpand
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Epigenetic inactivation of PLCD 1 in chronic myeloid leukemia
Phospholipase C δ1 (PLCD1), is located at the important tumor suppressor locus 3p22. It encodes an enzyme that mediates regulatory signaling of energy metabolism, calcium homeostasis andExpand
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