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A common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degeneration.
- G. Hageman, D. H. Anderson, +24 authors R. Allikmets
- Medicine, Biology
- Proceedings of the National Academy of Sciences…
- 17 May 2005
Age-related macular degeneration (AMD) is the most frequent cause of irreversible blindness in the elderly in developed countries. Our previous studies implicated activation of complement in the… Expand
INDOCYANINE GREEN VIDEOANGIOGRAPHY OF IDIOPATHIC POLYPOIDAL CHOROIDAL VASCULOPATHY
Purpose: To identify the precise choroidal abnormalities associated with idiopathic polypoidal choroidal vasculopathy (IPCV), patients with IPCV were examined with indocyanine green (ICG)… Expand
Dietary Carotenoids, Vitamins A, C, and E, and Advanced Age-Related Macular Degeneration
Objective. —To evaluate the relationships between dietary intake of carotenoids and vitamins A, C, and E and the risk of neovascular age-related macular degeneration (AMD), the leading cause of… Expand
Idiopathic macular telangiectasia.
- L. Yannuzzi, A. M. C. Bardal, K. B. Freund, K. Chen, C. Eandi, B. Blodi
- Archives of ophthalmology
- 1 April 2006
OBJECTIVES To review the frequency and nature of idiopathic macular telangiectasia and to classify the disorders based on new clinical and imaging observations. METHODS A combined retrospective and… Expand
The expanding clinical spectrum of idiopathic polypoidal choroidal vasculopathy.
- L. Yannuzzi, A. Ciardella, R. Spaide, M. Rabb, K. B. Freund, D. Orlock
- Archives of ophthalmology
- 1 April 1997
OBJECTIVE To expand the clinical spectrum of idiopathic polypoidal choroidal vasculopathy based on historical cases and newly recognized observations. METHODS A review of the previously reported 45… Expand
IDIOPATHIC POLYPOIDAL CHOROIDAL VASCULOPATHY (IPCV)
Eleven patients, 40 to 71 years old, had a choroidal vasculopathy that led to hemorrhagic and exudative macular degeneration. The patients had peculiar polypoidal, subretinal, vascular lesions… Expand
RETINAL ANGIOMATOUS PROLIFERATION IN AGE–RELATED MACULAR DEGENERATION
Background It is known that choroidal neovascularization (CNV) in age-related macular degeneration (ARMD) may erode through the retinal pigment epithelium, infiltrate the neurosensory retina, and… Expand
Polypoidal choroidal vasculopathy and neovascularized age-related macular degeneration.
OBJECTIVE To determine the nature and frequency of polypoidal choroidal vasculopathy (PCV) in a series of patients suspected of having neovascularized age-related macular degeneration (AMD). … Expand
Dietary fat and risk for advanced age-related macular degeneration.
OBJECTIVE To evaluate the relationship between intake of total and specific types of fat and risk for advanced age-related macular degeneration (AMD), the leading cause of irreversible blindness in… Expand
Polypoidal choroidal vasculopathy: a review.
- Yutaka Imamura, M. Engelbert, T. Iida, K. B. Freund, L. Yannuzzi
- Survey of ophthalmology
- 1 November 2010
More than a quarter century has passed since the original description of polypoidal choroidal vasculopathy (PCV) in 1982 as a peculiar hemorrhagic disorder involving the macula characterized by… Expand