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Effects of microinjections of Group II metabotropic glutamate agents into the amygdala on sleep
Systemic administration of the Group II metabotropic glutamate (mGlu) receptor agonist, LY379268 (LY37), dose-dependently suppresses rapid eye movement sleep (REM) whereas systemic administration ofExpand
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Effects of tetrodotoxin (TTX) inactivation of the central nucleus of the amygdala (CNA) on dark period sleep and activity
The amygdala has been implicated in emotional arousal and in the regulation of sleep. Previously, we demonstrated that tetrodotoxin (TTX), a sodium channel blocker that temporarily inactivatesExpand
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Influence of contextual fear on sleep in mice: a strain comparison.
STUDY OBJECTIVES This study assessed the influence of contextual fear on sleep in inbred and hybrid mouse strains. DESIGN Uninterrupted baseline recordings of sleep were obtained for 3 days in 3Expand
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Differential effects of controllable and uncontrollable footshock stress on sleep in mice.
STUDY OBJECTIVES Inescapable shock (IS), an uncontrollable stressor, and presentation of fearful contexts associated with IS produce prominent reductions in REM sleep. We compared sleep in animalsExpand
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Rat strain differences in freezing and sleep alterations associated with contextual fear.
STUDY OBJECTIVE To examine rat strain differences in fear responses and subsequent alterations in sleep associated with contextual fear. DESIGN Recordings for each strain were obtained ofExpand
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Antagonizing corticotropin-releasing factor in the central nucleus of the amygdala attenuates fear-induced reductions in sleep but not freezing.
STUDY OBJECTIVES Contextual fear is followed by significant reductions in rapid eye movement sleep (REM) that are regulated by the central nucleus of the amygdala (CNA). Corticotropin-releasingExpand
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Individual variation in sleep and motor activity in rats
We examined individual differences in sleep and motor activity across 2 consecutive days in rats. EEG and motor activity were recorded via telemetry in Wistar rats (n=29) for 48h underExpand
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Influence of tetrodotoxin inactivation of the central nucleus of the amygdala on sleep and arousal.
STUDY OBJECTIVES To determine the effects of temporary functional inactivation of the central nucleus of the amygdala on sleep and on activity in an arousing environment, an open field. DESIGN RatsExpand
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Rat strain differences in sleep after acute mild stressors and short-term sleep loss
Genetic and physiological diversity amongst rodent strains provide the potential for developing models that may give insight into factors that regulate sleep in response to environmental challenges.Expand
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Interactions between brief restraint, novelty and footshock stress on subsequent sleep and EEG power in rats
Stress produces significant alterations in sleep that appear to vary with the type, intensity and duration of the stressor. Brief manual restraint may be stressful in rodents but is often requiredExpand
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