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Mitochondrial polymorphisms as risk factors for endometrial cancer in southwest China
  • L. Xu, Y. Hu, +4 authors C. Xiao
  • Biology, Medicine
  • International journal of gynecological cancer…
  • 1 July 2006
It is just in recent years that mitochondrial DNA (mtDNA) mutations have been found in solid tumors. Although a direct link between the presence of mtDNA mutations and the development of tumors hasExpand
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Tri-ortho-cresyl phosphate induces autophagy of rat spermatogonial stem cells.
Tri-ortho-cresyl phosphate (TOCP) has been widely used as plasticizers, plastic softeners, and flame retardants in industry and reported to have a deleterious effect on the male reproductive systemExpand
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CXCL16 upregulates RANKL expression in rheumatoid arthritis synovial fibroblasts through the JAK2/STAT3 and p38/MAPK signaling pathway
ObjectiveTo explore the influence of chemokine, CXCL16, on the expression of the receptor activator nuclear factor κB ligand (RANKL) in rheumatoid arthritis (RA) fibroblast-like synoviocytesExpand
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Recovery of a chemically synthesized Japanese encephalitis virus reveals two critical adaptive mutations in NS2B and NS4A.
  • X. Li, X. Li, +11 authors B. Zhang
  • Biology, Medicine
  • The Journal of general virology
  • 1 April 2014
A full-length genome infectious clone is a powerful tool for functional assays in virology. In this study, using a chemical synthesized complete genome of Japanese encephalitis virus (JEV) strainExpand
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Abnormal expression of P2X family receptors in Chinese pediatric acute leukemias.
Nucleotides are new players in intercellular communication network. P2X family receptors are ATP-gated plasma membrane ion channels with diverse biological functions. Their distribution patterns andExpand
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Involvement of c-Src/STAT3 signal in EGF-induced proliferation of rat spermatogonial stem cells
Epidermal growth factor (EGF) plays a role in male germ cell development, but the precise function is yet to be defined. This study shows that EGF stimulates rat spermatogonial proliferation in aExpand
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Abnormal expression of ADAR1 isoforms in Chinese pediatric acute leukemias.
The posttranscriptional RNA editing by the type 1 adenosine deaminase acting on RNAs (ADAR1), expressed as p110 and p150 isoforms, is important for both physiological and pathological processes.Expand
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[Expression of HER2/neu in meningiomas: an immunohistochemistry and fluorescence in situ hybridization study].
OBJECTIVE To investigate the expression of HER2/neu, Ki-67 and TK1 protein in meningiomas in correlation with tumor grades and recurrence. METHODS Twenty cases of each of the following types ofExpand
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Stattic inhibits RANKL‐mediated osteoclastogenesis by suppressing activation of STAT3 and NF‐&kgr;B pathways
&NA; Tofacitinib, a small molecule JAK inhibitor, has been widely used to reduce inflammation and inhibit progression of bone destruction in rheumatoid arthritis. STAT3, a downstream signalingExpand
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Metformin alleviates renal injury in diabetic rats by inducing Sirt1/FoxO1 autophagic signal axis
Diabetic nephropathy (DN) is the major microvascular complication of diabetes mellitus and the most important cause of end‐stage renal disease worldwide. Metformin is the preferred oral hypoglycaemicExpand
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