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Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal.
The embryonic stem cell (ESC) transcriptional and epigenetic networks are controlled by a multilayer regulatory circuitry, including core transcription factors (TFs), posttranscriptional modifierExpand
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Role of oxidative stress in myocardial hypertrophy and failure.
see Ref. 9). Recent progress in understanding the Introduction mechanisms that mediate myocardial remodeling at the cellular level has led to evidence that reactive In the setting of hemodynamicExpand
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Generation of pig induced pluripotent stem cells with a drug-inducible system.
Domesticated ungulate pluripotent embryonic stem (ES) cell lines would be useful for generating precise gene-modified animals. To date, many efforts have been made to establish domesticated ungulateExpand
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Activin A Maintains Self‐Renewal and Regulates Fibroblast Growth Factor, Wnt, and Bone Morphogenic Protein Pathways in Human Embryonic Stem Cells
Human embryonic stem cells (hESCs) self‐renew indefinitely while maintaining pluripotency. The molecular mechanism underlying hESCs self‐renewal and pluripotency is poorly understood. To identify theExpand
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Novel Role for JNK as a Stress-activated Bcl2 Kinase*
Interleukin (IL)-3-induced Bcl2 phosphorylation at Ser70 may be required for its full and potent antiapoptotic activity. However, in the absence of IL-3, increased expression of Bcl2 can also prolongExpand
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Combinatorial Signals of Activin/Nodal and Bone Morphogenic Protein Regulate the Early Lineage Segregation of Human Embryonic Stem Cells*S⃞
Cell fate commitment of pre-implantation blastocysts, to either the inner cell mass or trophoblast, is the first step in cell lineage segregation of the developing human embryo. However, theExpand
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Nested codes with multiple interpretations
This paper proposes a new approach to channel code design for wireless network applications. Expand
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MEK1/2-ERK1/2 mediates alpha1-adrenergic receptor-stimulated hypertrophy in adult rat ventricular myocytes.
We examined the relative roles of the mitogen-activated protein kinases (MAPK) in mediating the alpha1-adrenergic receptor (alpha1-AR) stimulated hypertrophic phenotype in adult rat ventricularExpand
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E‐Cadherin‐Mediated Cell–Cell Contact Is Critical for Induced Pluripotent Stem Cell Generation
The low efficiency of reprogramming and genomic integration of virus vectors obscure the potential application of induced pluripotent stem (iPS) cells; therefore, identification of chemicals andExpand
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Delayed cardioprotection by intestinal preconditioning is mediated by calcitonin gene-related peptide.
Previous studies have shown that nitric oxide and calcitonin gene-related peptide (CGRP) are involved in mediation of the delayed cardioprotection of ischemic or pharmacological preconditioning, andExpand
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