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The Role of Hypoxia-Inducible Factor 1α in Determining the Properties of Castrate-Resistant Prostate Cancers
Background Castrate-resistant prostate cancer (CRPC) is a lethal condition in patients receiving androgen deprivation therapy for prostate cancer (PC). Despite numerous studies showing the expressionExpand
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miR‐125b regulates the proliferation of glioblastoma stem cells by targeting E2F2
microRNAs (miRNAs) play important role in regulating cancer stem cell self‐renewal and differentiation, but the expression prolife of miRNAs in glioma stem cells (GSCs) has not been addressed. Here,Expand
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MicroRNA-9 Mediates the Cell Apoptosis by Targeting Bcl2l11 in Ischemic Stroke
Ischemic strokes occur as a result of an obstruction within a blood vessel supplying blood to the brain and accounts for about 87 % of all cases. During the cerebral ischemia, most of the neuronsExpand
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Interaction between single molecules of Mac-1 and ICAM-1 in living cells: an atomic force microscopy study.
The interaction between integrin macrophage differentiation antigen associated with complement three receptor function (Mac-1) and intercellular adhesion molecule-1 (ICAM-1), which is controlledExpand
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Bis(2,3-dibromo-4,5-dihydroxybenzyl) Ether, a Marine Algae Derived Bromophenol, Inhibits the Growth of Botrytis cinerea and Interacts with DNA Molecules
Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether (BDDE) is a bromophenol isolated from marine algae. Previous reports have shown that BDDE possesses cytotoxic and antibacterial activity. In the presentExpand
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Melittin prevents liver cancer cell metastasis through inhibition of the Rac1‐dependent pathway
Melittin, a water‐soluble toxic peptide derived from bee venom of Apis mellifera was reported to have inhibitory effects on hepatocellular carcinoma (HCC). However, its role in antimetastasis and theExpand
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Rapid activation of JNK and p38 by glucocorticoids in primary cultured hippocampal cells
Rapid activation of JNK and p38 and their translocation to the cell nucleus by glucocorticoids, corticosterone (Cort), and bovine serum‐conjugated corticosterone (Cort‐BSA) were studied in primaryExpand
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Gastrin increases its own synthesis in gastrointestinal cancer cells via the CCK2 receptor
The involvement of the gastrointestinal hormone gastrin in the development of gastrointestinal cancer is highly controversial. Here we demonstrate a positive‐feedback loop whereby gastrin, acting viaExpand
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Effectiveness of dietary xylo-oligosaccharides for broilers fed a conventional corn-soybean meal diet
An experiment was conducted to investigate the effect of dietary supplementation of xylo-oligosaccharides (XOS) on growth performance, meat quality, immune functions, duodenal morphology andExpand
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Hydrogen Sulfide Improves Endothelial Dysfunction via Downregulating BMP4/COX-2 Pathway in Rats with Hypertension
Aims. We object to elucidate that protective effect of H2S on endothelium is mediated by downregulating BMP4 (bone morphogenetic protein 4)/cyclooxygenase- (COX-) 2 pathway in rats with hypertension.Expand
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