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Gene expression profiling of breast cell lines identifies potential new basal markers
A better molecular characterization of breast cell lines (BCL) may help discover new markers to apply to tumour samples. We performed gene and protein expression profiling of 31 BCL using… Expand
Mutations of polycomb‐associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia
- V. Gelsi-Boyer, V. Trouplin, +13 authors D. Birnbaum
- Biology, Medicine
- British journal of haematology
- 1 June 2009
The myelodysplastic syndromes (MDSs) are a heterogeneous group of clonal haematological diseases characterized by ineffective haematopoiesis and predisposition to acute myeloid leukaemia (AML). The… Expand
Gene expression profiling identifies molecular subgroups among nodal peripheral T-cell lymphomas
The classification of peripheral T-cell lymphomas (PTCL) is still a matter of debate. To establish a molecular classification of PTCL, we analysed 59 primary nodal T-cell lymphomas using cDNA… Expand
Impact of Expert Pathologic Review of Lymphoma Diagnosis: Study of Patients From the French Lymphopath Network.
- C. Laurent, M. Baron, +47 authors P. Gaulard
- Journal of clinical oncology : official journal…
- 1 May 2017
Purpose To prospectively assess the clinical impact of expert review of lymphoma diagnosis in France. Materials and Methods From January 2010 to December 2013, 42,145 samples from patients with newly… Expand
Correlated break at PARK2/FRA6E and loss of AF-6/Afadin protein expression are associated with poor outcome in breast cancer
Common fragile sites (CFSs) are regions of chromosomal break that may play a role in oncogenesis. The most frequent alteration occurs at FRA3B, within the FHIT gene, at chromosomal region 3p14. We… Expand
The co-receptor BTLA negatively regulates human Vγ9Vδ2 T-cell proliferation: a potential way of immune escape for lymphoma cells.
Vγ9Vδ2 cells, the major γδ T-cell subset in human peripheral blood, represent a T-cell subset that displays reactivity against microbial agents and tumors. The biology of Vγ9Vδ2 T cells remains… Expand
Prognosis and Gene Expression Profiling of 20q13-Amplified Breast Cancers
- C. Ginestier, N. Cervera, +10 authors F. Bertucci
- Biology, Medicine
- Clinical Cancer Research
- 1 August 2006
Purpose: Amplification of chromosomal region 20q13 occurs in breast cancer but remains poorly characterized. Experimental Design: To establish the frequency of 20q13 amplification and select the… Expand
B-cell non-Hodgkin lymphoma linked to Coxiella burnetii.
Bacteria can induce human lymphomas, whereas lymphoproliferative disorders have been described in patients with Q fever. We observed a lymphoma in a patient with Q fever that prompted us to… Expand
Rituximab plus Lenalidomide in Advanced Untreated Follicular Lymphoma
- F. Morschhauser, N. Fowler, +31 authors G. Salles
- The New England journal of medicine
- 6 September 2018
BACKGROUND Rituximab plus chemotherapy has been shown to be effective in patients with advanced‐stage, previously untreated follicular lymphoma; nevertheless, most patients will have a relapse.… Expand
Identification of MUM1 as a prognostic immunohistochemical marker in follicular lymphoma using computerized image analysis.
Detection of MUM1+ cells in follicular lymphoma (FL) tissues was previously found to be associated with poor prognosis in a single report, whereas the usefulness of Ki-67 immunostaining remains… Expand