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The DNA sequence of the human X chromosome
The human X chromosome has a unique biology that was shaped by its evolution as the sex chromosome shared by males and females. We have determined 99.3% of the euchromatic sequence of the XExpand
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A direct brainstem–amygdala–cortical ‘alarm’ system for subliminal signals of fear
We examined whether consciously undetected fear signals engage a collateral brainstem pathway to the amygdala and prefrontal cortex in the intact human brain, using functional neuroimaging. Expand
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The ‘when’ and ‘where’ of perceiving signals of threat versus non-threat
We tested the proposal that signals of potential threat are given precedence over positive and neutral signals, reflected in earlier and more pronounced changes in neural activity. Expand
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Interactions between BDNF Val66Met polymorphism and early life stress predict brain and arousal pathways to syndromal depression and anxiety
Individual risk markers for depression and anxiety disorders have been identified but the explicit pathways that link genes and environment to these markers remain unknown. Here we examined theExpand
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Brain maturation in adolescence: Concurrent changes in neuroanatomy and neurophysiology
Adolescence to early adulthood is a period of dramatic transformation in the healthy human brain. However, the relationship between the concurrent structural and functional changes remains unclear.Expand
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A Temporal Dissociation of Subliminal versus Supraliminal Fear Perception: An Event-related Potential Study
Current theories of emotion suggest that threat-related stimuli are first processed via an automatically engaged neural mechanism, which occurs outside conscious awareness. This mechanism operates inExpand
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The Mellow Years?: Neural Basis of Improving Emotional Stability over Age
Contrary to the pervasive negative stereotypes of human aging, emotional functions may improve with advancing age. However, the brain mechanisms underlying changes in emotional function over ageExpand
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Misinterpreting Emotional Expressions in Attention-Deficit/Hyperactivity Disorder: Evidence for a Neural Marker and Stimulant Effects
BACKGROUND In addition to cognitive impairment, there are disruptions to mood and emotion processing in attention-deficit/hyperactivity disorder (ADHD) but little is known about their neural basis.Expand
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Early Life Stress and Morphometry of the Adult Anterior Cingulate Cortex and Caudate Nuclei
BACKGROUND Early life stress (ELS) is linked to adult psychopathology and may contribute to long-term brain alterations, as suggested by studies of women who suffered childhood sexual abuse. WeExpand
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Small‐world properties of nonlinear brain activity in schizophrenia
A disturbance in the interactions between distributed cortical regions may underlie the cognitive and perceptual dysfunction associated with schizophrenia. In this article, nonlinear measures ofExpand
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