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Brief Intervention for Prenatal Alcohol Use: A Randomized Trial
OBJECTIVE: To test the effectiveness of a brief intervention in the reduction of prenatal alcohol consumption by women when a partner is included. METHODS: Randomized trial of a single session briefExpand
Predictors of Technical Success and Postnatal Biventricular Outcome After In Utero Aortic Valvuloplasty for Aortic Stenosis With Evolving Hypoplastic Left Heart Syndrome
Background— Aortic stenosis in the midgestation fetus with a normal-sized or dilated left ventricle predictably progresses to hypoplastic left heart syndrome when associated with certainExpand
Brief intervention for alcohol use in pregnancy: a randomized trial.
AIMS To assess the impact of a brief intervention on antepartum alcohol consumption. DESIGN A randomized clinical trial. SETTING The obstetrics practices of the Brigham and Women's Hospital inExpand
Toluene embryopathy: clinical delineation and developmental follow-up.
OBJECTIVE To expand the phenotype of toluene embryopathy. METHOD Review of case records of 35 deliveries with antenatal exposure to toluene. Six children were examined and their features areExpand
Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome: Postnatal Outcomes of the First 100 Patients
Background— Fetal aortic valvuloplasty can be performed for severe midgestation aortic stenosis in an attempt to prevent progression to hypoplastic left heart syndrome (HLHS). A subset of patientsExpand
GPC3 mutation analysis in a spectrum of patients with overgrowth expands the phenotype of Simpson-Golabi-Behmel syndrome.
Simpson-Golabi-Behmel syndrome (SGBS) is an X-linked overgrowth syndrome caused by deletions in glypican 3 (GPC3). SGBS is characterized by pre- and postnatal overgrowth, a characteristic facialExpand
Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies
Noninvasive prenatal testing (NIPT) or cell-free DNA (cfDNA) screening can be used to screen for common fetal autosomal aneuploidies. However, NIPT is not a diagnostic test, as cfDNA in the plasma ofExpand
Use of array comparative genomic hybridization for prenatal diagnosis of fetuses with sonographic anomalies and normal metaphase karyotype
To prospectively study the addition of array comparative genomic hybridization (CGH) to the prenatal evaluation of fetal structural anomalies.
Teratogen update: toluene.
Extrapolating from animal data, at the level at which well-controlled occupational exposure to toluene vapor is encountered, in utero exposure does not pose a significant fetal risk. However,Expand
Fetal Fatty Acid Oxidation Defects and Maternal Liver Disease in Pregnancy
OBJECTIVE: The objective was to evaluate the relationships between all types of fetal fatty acid oxidation defects and maternal liver disease, including acute fatty liver of pregnancy and hemolysis,Expand