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Evolution of genomic content in the stepwise emergence of Escherichia coli O157:H7.
Genome comparisons have demonstrated that dramatic genetic change often underlies the emergence of new bacterial pathogens. Evolutionary analysis of Escherichia coli O157:H7, a pathogen that has… Expand
Short- and long-term changes in proteome composition and kinetic properties in a culture of Escherichia coli during transition from glucose-excess to glucose-limited growth conditions in continuous…
To investigate the ability of Escherichia coli K12 MG1655 to cope with excess and limitation of a carbon and energy source, we studied the changes in kinetic properties and two-dimensional (2D) gel… Expand
On-chip non-equilibrium dissociation curves and dissociation rate constants as methods to assess specificity of oligonucleotide probes
- L. Wick, J. Rouillard, T. Whittam, E. Gulari, J. Tiedje, S. Hashsham
- Biology, Medicine
- Nucleic acids research
- 13 February 2006
Nucleic acid hybridization serves as backbone for many high-throughput systems for detection, expression analysis, comparative genomics and re-sequencing. Specificity of hybridization between probes… Expand
The apparent clock-like evolution of Escherichia coli in glucose-limited chemostats is reproducible at large but not at small population sizes and can be explained with Monod kinetics.
To follow and model evolution of a microbial population in the chemostat, parameters are needed that give an indication of the absolute extent of evolution at a high resolution of time. In this study… Expand
Molecular components of physiological stress responses in Escherichia coli.
In order to survive under and adapt to different conditions Escherichia coli has evolved elaborate systems that are able to sense and respond to environmental stimuli. Very often, different stresses… Expand
Genetic diversity in Campylobacter jejuni is associated with differential colonization of broiler chickens and C57BL/6J IL10-deficient mice
Previous studies have demonstrated that Campylobacter jejuni, the leading causative agent of bacterial food-borne disease in the USA, exhibits high-frequency genetic variation that is associated with… Expand
Global transcriptional response of Escherichia coli O157:H7 to growth transitions in glucose minimal medium
- T. Bergholz, L. Wick, W. Qi, J. T. Riordan, L. Ouellette, T. Whittam
- Biology, Medicine
- BMC Microbiology
- 29 October 2007
Background:Global patterns of gene expression of Escherichia coli K-12 during growth transitions have been deeply investigated, however, comparable studies of E. coli O157:H7 have not been explored,… Expand
Ultrasensitive Detection of Salmonella and Listeria monocytogenes by Small-Molecule Chemiluminescence Probes.
- Michal E Roth-Konforti, Ori Green, +7 authors D. Shabat
- Chemistry, Medicine
- Angewandte Chemie
- 22 July 2019
Detection of Salmonella and L. monocytogenes in food samples by current diagnostic methods requires relatively long time to results (2-6 days). Furthermore, the ability to perform environmental… Expand
Genomic diversity of pathogenic Escherichia coli of the EHEC 2 clonal complex
BackgroundEvolutionary analyses of enterohemorrhagic Escherichia coli (EHEC) have identified two distantly related clonal groups: EHEC 1, including serotype O157:H7 and its inferred ancestor O55:H7;… Expand
Virulence factor activity relationships: challenges and development approaches.
- Dieter M. Tourlousse, R. Stedtfeld, Samuel W Baushke, L. Wick, S. Hashsham
- Medicine, Chemistry
- Water environment research : a research…
- 1 March 2007
Virulence factor activity relationships (VFAR) is a predictive approach proposed by the National Research Council's Committee on Drinking Water Contaminants (Washington, D.C.) to classify and rank… Expand