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Identification of somatic mutations in non-small cell lung carcinomas using whole-exome sequencing.
Several highly mutated genes identified in the study are promising druggable targets in cancer therapy including ALK, CTNNA3, DCC, MLL3, PCDHIIX, Pik3C2B, PIK3CG and ROCK2. Expand
Genetic variants and risk of lung cancer in never smokers: a genome-wide association study.
Genetic variants at 13q31.3 alter the expression of GPC5, and are associated with susceptibility to lung cancer in never smokers, and a cis eQTL analysis showed there was a strong correlation between genotypes of the replicated SNPs and the transcription level of the gene GPC 5 in normal lung tissues. Expand
Saccharopolyspora flava sp. nov. and Saccharopolyspora thermophila sp.nov., novel actinomycetes from soil.
The generic position of two aerobic, Gram-positive, non-acid-alcohol-fast actinomycetes was established following the isolation of their PCR-amplified 16S rRNA genes and alignment of the resultantExpand
Olivibacter soli sp. nov., Olivibacter ginsengisoli sp. nov. and Olivibacter terrae sp. nov., from soil of a ginseng field and compost in South Korea.
Three novel strains, designated Gsoil 034T, G soil 060T and Jip13T, isolated from soil from a ginseng field and compost in South Korea, were characterized using a polyphasic approach to clarify their taxonomic positions and supported the affiliation of these strains to the genus Olivibacter. Expand
Histone Modifications Regulate Chromatin Compartmentalization by Contributing to a Phase Separation Mechanism.
The data suggest a general mechanism by which histone marks regulate chromosome compartmentalization by promoting phase separation, and are reminiscent of heterochromatin as they are highly dense chromatin-containing structures that are resistant to DNase and exclude the general transcription factor TFIIB. Expand
Arabidopsis FLL2 promotes liquid–liquid phase separation of polyadenylation complexes
It is shown that coiled-coil proteins can promote liquid–liquid phase separation, which expands the understanding of the principles that govern the in vivo dynamics of liquid-like bodies. Expand
Physiological characterization of maize tolerance to low dose of aluminum, highlighted by promoted leaf growth
The Al-promoted leaf growth is likely a result of increased protein synthesis, a lowered Ca++ level, and the discharge of the growth-inhibitory factors, and may be a ‘memory’ effect caused by the earlier AS in maize. Expand
AGTR2, One Possible Novel Key Gene for the Entry of SARS-CoV-2 Into Human Cells
Simulation of 3D structure based protein-protein interaction reveals that AGTR2 (angiotensin II receptor type 2), a G-protein coupled receptor, has interaction with SARS-CoV-2 and is highly expressed in lung with a high tissue specificity, and it is suggested that <italic>AGTR2</italic/> could be a putative novel gene for the entry of Sars-Cov-2 into human cells. Expand
The molluscan HSP70s and their expression in hemocytes
This chapter reviews the recent research progress about the diversity of molluscan HSP70 family members, their sequence characters and expression profiles in hemocytes under various stressors. Expand
Phycicoccus ginsenosidimutans sp. nov., isolated from soil of a ginseng field.
The chemotaxonomic data and the high genomic DNA G+C content of strain BXN5-13(T) supported its affiliation with the genus Phycicoccus, and it represents a novel species within the genusPhycimutans sp. Expand