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Parent–progeny sequencing indicates higher mutation rates in heterozygotes
Mutation rates vary within genomes, but the causes of this remain unclear. As many prior inferences rely on methods that assume an absence of selection, potentially leading to artefactual results, weExpand
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An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED.
Polycomb repressive complex 2 (PRC2) consists of three core subunits, EZH2, EED and SUZ12, and plays pivotal roles in transcriptional regulation. The catalytic subunit EZH2 methylates histone H3Expand
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Mutation rate analysis via parent–progeny sequencing of the perennial peach. I. A low rate in woody perennials and a higher mutagenicity in hybrids
Mutation rates vary between species, between strains within species and between regions within a genome. What are the determinants of these forms of variation? Here, via parent–offspring sequencingExpand
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Discovery of discriminatory quality control markers for Chinese herbal medicines and related processed products by combination of chromatographic analysis and chemometrics methods: Radix Scutellariae
  • F. Wang, B. Wang, +4 authors H. Li
  • Chemistry, Medicine
  • Journal of pharmaceutical and biomedical analysis
  • 10 May 2017
&NA; The processing procedure of traditional Chinese herbal medicines (CHMs) plays an essential role in clinical applications. However, little progress has been made on the quality control of crudeExpand
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Identification of miRNAs involved in pear fruit development and quality
BackgroundMicroRNAs (miRNAs) are a class of small, endogenous RNAs that take part in regulating genes through mediating gene expressions at the post-transcriptional level in plants. Previous studiesExpand
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Two FERONIA-like receptor (FLR) genes are required to maintain architecture, fertility, and seed yield in rice
The Arabidopsis gene FERONIA (FER) regulates cell elongation and fertility. Although the function of FER in promoting plant growth and regulating fructification in dicotyledon Arabidopsis has beenExpand
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Evolutionary dynamics on graphs: Efficient method for weak selection.
Investigating the evolutionary dynamics of game theoretical interactions in populations where individuals are arranged on a graph can be challenging in terms of computation time. Here, we propose anExpand
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Aspiration dynamics of multi-player games in finite populations
On studying strategy update rules in the framework of evolutionary game theory, one can differentiate between imitation processes and aspiration-driven dynamics. In the former case, individualsExpand
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Bacterial community structure in intertidal sediments of Fildes Peninsula, maritime Antarctica
The Fildes Peninsula has a maritime Antarctic climate and has attracted the interest of scientists for decades. The soil bacterial community and the environmental factors shaping it have been wellExpand
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Molecular cloning and functional characterization of an ATP-binding cassette transporter OtrC from Streptomyces rimosus
BackgroundThe otrC gene of Streptomyces rimosus was previously annotated as an oxytetracycline (OTC) resistance protein. However, the amino acid sequence analysis of OtrC shows that it is a putativeExpand
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