• Publications
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Genome and proteome of long-chain alkane degrading Geobacillus thermodenitrificans NG80-2 isolated from a deep-subsurface oil reservoir
  • L. Feng, W. Wang, +9 authors L. Wang
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 27 March 2007
The complete genome sequence of Geobacillus thermodenitrificans NG80-2, a thermophilic bacillus isolated from a deep oil reservoir in Northern China, consists of a 3,550,319-bp chromosome and aExpand
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Human marrow stromal cell therapy for stroke in rat: Neurotrophins and functional recovery
ObjectiveTo test the effect of IV-injected human bone marrow stromal cells (hMSC) on neurologic functional deficits after stroke in rats. Methods Rats were subjected to transient middle cerebralExpand
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Spinal cord injury in rat: treatment with bone marrow stromal cell transplantation
We tested the hypothesis that transplantation of bone marrow stromal cells (MSCs) into the spinal cord after a contusion injury promotes functional outcome. Rats (n = 31) were subjected to a weightExpand
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Mesenchymal Stem Cell-Based Tissue Regeneration is Governed by Recipient T Lymphocyte via IFN-γ and TNF-α
Stem cell–based regenerative medicine is a promising approach in tissue reconstruction. Here we show that proinflammatory T cells inhibit the ability of exogenously added bone marrow mesenchymal stemExpand
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Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat
  • J. Chen, Y. Li, +6 authors M. Chopp
  • Biology, Medicine
  • Journal of neuroscience research
  • 15 September 2003
The present study investigates the induction of neurogenesis, reduction of apoptosis, and promotion of basic fibroblast growth factor (bFGF) expression as possible mechanisms by which treatment ofExpand
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Intravenous Administration of Human Bone Marrow Stromal Cells Induces Angiogenesis in the Ischemic Boundary Zone After Stroke in Rats
Abstract— We tested the hypothesis that intravenous infusion of human bone marrow stromal cells (hMSCs) promotes vascular endothelial growth factor (VEGF) secretion, VEGF receptor 2 (VEGFR2)Expand
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A biosynthetic pathway for anandamide
  • J. Liu, L. Wang, +8 authors G. Kunos
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences
  • 5 September 2006
The endocannabinoid arachidonoyl ethanolamine (anandamide) is a lipid transmitter synthesized and released “on demand” by neurons in the brain. Anandamide is also generated by macrophages where itsExpand
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Klotho Inhibits Transforming Growth Factor-β1 (TGF-β1) Signaling and Suppresses Renal Fibrosis and Cancer Metastasis in Mice*
Fibrosis is a pathological process characterized by infiltration and proliferation of mesenchymal cells in interstitial space. A substantial portion of these cells is derived from residingExpand
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Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke
We demonstrate that the 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A (HMG‐CoA) reductase inhibitors atorvastatin and simvastatin enhance functional outcome and induce brain plasticity when administeredExpand
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Regulation of hepcidin transcription by interleukin-1 and interleukin-6.
Hepcidin is a peptide that regulates iron homeostasis by inhibiting iron absorption by the small intestine and release of iron from macrophages. Its production is stimulated by iron overload and byExpand
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