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A common Fanconi anemia mutation in black populations of sub-Saharan Africa.
Fanconi anemia (FA) is a genetically heterogeneous chromosomal instability syndrome associated with multiple congenital abnormalities, aplastic anemia, and cancer. We report that a deletion mutationExpand
Kaposi sarcoma in South African children
The incidence of Kaposi's sarcoma (KS) in sub‐Saharan Africa, increased tens of times since the onset of the AIDS epidemic. There is, however, very little literature concerning the clinical featuresExpand
Hepatocellular carcinoma and liver tumors in South African children
The high regional incidence of hepatocellular carcinoma (HCC) in South Africa also may be present in children of the region, although the link to hepatitis B (HBV) appears less clear. The objectiveExpand
The Saint Siluan warning signs of cancer in children: Impact of education in rural South Africa
Two thirds of children with cancer never reach a specialist centre for treatment in South Africa. The majority of those who present have advanced disease. A campaign was undertaken to educate theExpand
Kaposi sarcoma in South African children
This article has been published as part of Infectious Agents and Cancer Volume 5 Supplement 1, 2010: Proceedings of the 12th International Conference on Malignancies in AIDS and Other Acquired Expand
Malignant Liver Tumors in South African Children: A National Audit
BackgroundMalignant liver tumors (mostly hepatoblastoma [HB] and hepatocellular carcinoma [HCC]) are uncommon, representing 0.5%–2% of childhood malignancies worldwide. The pattern of liver tumorsExpand
Infection with human immunodeficiency virus‐1 (HIV) among children with cancer in South Africa
HIV increases the risk of certain cancers known, or thought, to have an underlying infectious etiology; the impact on the risk of cancer in children is less clear.
Paroxysmal nocturnal hemoglobinuria arising from Fanconi anemia.
The progress of a female child with African type Fanconi anemia that evolves in time into paroxysmal nocturnal hemoglobinuria is described. Modern diagnostic methods are used to confirm this process.Expand
A 20-Year Retrospective Review of Retinoblastoma at Two Tertiary Academic Hospitals in Johannesburg, South Africa
Aim: This paper presents a 20-year review of retinoblastoma in Johannesburg, South Africa, aiming to better characterize the disease in this sub-Saharan setting. Methods: The study represents aExpand