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KID-1, a Protein Kinase Induced by Depolarization in Brain*
Membrane depolarization leads to changes in gene expression that modulate neuronal plasticity. Using representational difference analysis, we have identified a previously undiscovered cDNA, KID-1Expand
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The Urokinase Plasminogen Activator Receptor (UPAR) Is Preferentially Induced by Nerve Growth Factor in PC12 Pheochromocytoma Cells and Is Required for NGF-Driven Differentiation
Nerve growth factor (NGF)-driven differentiation of PC12 pheochromocytoma cells is a well studied model used both to identify molecular, biochemical, and physiological correlates ofExpand
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Testosterone regulation of proopiomelanocortin messenger ribonucleic acid in the arcuate nucleus of the male rat.
GnRH regulates the secretion of LH and FSH, which stimulate the secretion of testicular hormones. Acting in a reciprocal fashion, these hormones, including testosterone and inhibin, exert a negativeExpand
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Sex differences in vasopressin neurons in the bed nucleus of the stria terminalis by in situ hybridization
To determine whether a sex difference exists in the biosynthetic capacity of vasopressingergic (AVP) neurons in the bed nucleus of the stria terminalis (BNST), we have used in situ hybridization andExpand
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Two synaptotagmin genes, Syt1 and Syt4, are differentially regulated in adult brain and during postnatal development following kainic acid-induced seizures.
The synaptotagmins together with other vesicle proteins are thought to be essential for the docking and/or fusion of synaptic vesicles with the plasma membrane that occurs following depolarizationExpand
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Expression of the urokinase plasminogen activator receptor is transiently required during “priming” of PC12 cells in nerve growth factor‐directed cellular differentiation
We previously identified the urokinase plasminogen activator receptor (UPAR) as a gene induced by nerve growth factor (NGF), but not by epidermal growth factor (EGF), in PC12 cells (Farias‐Eisner etExpand
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Reduced preprosomatostatin messenger ribonucleic acid in the periventricular nucleus of hypophysectomized rats determined by quantitative in situ hybridization.
Physiological evidence suggests that somatostatin (SS) inhibits the release of GH and TSH from the anterior pituitary and that elements of these two systems may feed back to regulate hypothalamic SSExpand
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Differential localization of two glutamic acid decarboxylases (GAD65 and GAD67) in adult monkey visual cortex
Adult monkey primary visual cortex contains a diverse population of stellate neurons that utilize the neurotransmitter γ aminobutyric acid (GABA). Two glutamic acid decarboxylase (GAD) enzymes thatExpand
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Seizure activity induces PIM‐1 expression in brain
We recently identified KID‐1, a previously undescribed protein kinase induced by depolarization in PC12 cells and brain (Feldman et al., 1998). KID‐1 shares a high degree of sequence homology withExpand
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Regulation of somatostatin and growth hormone-releasing hormone gene expression in the rat brain.
We have studied the regulation of somatostatin (SS) and growth hormone-releasing hormone (GHRH) gene expression in the brain of the laboratory rat. We report that hypophysectomy in the adult maleExpand
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