L. Veldeman

Publications82
h-index14
Citations1,036
Highly Influential Citations40
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Evidence behind use of intensity-modulated radiotherapy: a systematic review of comparative clinical studies.
Since its introduction more than a decade ago, intensity-modulated radiotherapy (IMRT) has spread to most radiotherapy departments worldwide for a wide range of indications. The technique has been… Expand
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Hypofractionated whole breast irradiation for patients with large breasts: a randomized trial comparing prone and supine positions.
BACKGROUND AND PURPOSE Comparison of acute toxicity of whole-breast irradiation (WBI) in prone and supine positions. MATERIALS AND METHODS This non-blinded, randomized, prospective, mono-centric… Expand
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Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose and association with genetic polymorphisms in DNA DSB repair genes.
PURPOSE To investigate the association between dose-related parameters and polymorphisms in DNA DSB repair genes XRCC3 (c.-1843A>G, c.562-14A>G, c.722C>T), Rad51 (c.-3429G>C, c.-3392G>T), Lig4… Expand
  • 103
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Factors modifying the risk for developing acute skin toxicity after whole-breast intensity modulated radiotherapy
BackgroundAfter breast-conserving radiation therapy most patients experience acute skin toxicity to some degree. This may impair patients’ quality of life, cause pain and discomfort. In this study,… Expand
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Alternated prone and supine whole-breast irradiation using IMRT: setup precision, respiratory movement and treatment time.
PURPOSE The objective of this study was to compare setup precision, respiration-related breast movement and treatment time between prone and supine positions for whole-breast irradiation. METHODS… Expand
  • 38
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Radiation-induced lung damage promotes breast cancer lung-metastasis through CXCR4 signaling
Radiotherapy is a mainstay in the postoperative treatment of breast cancer as it reduces the risks of local recurrence and mortality after both conservative surgery and mastectomy. Despite recent… Expand
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Preliminary results on setup precision of prone-lateral patient positioning for whole breast irradiation.
PURPOSE The aim of this study was to develop a rapid and reproducible technique for prone positioning and to compare dose-volume indices in prone and supine positions. METHODS AND MATERIALS… Expand
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Heart dose reduction by prone deep inspiration breath hold in left-sided breast irradiation.
BACKGROUND AND PURPOSE Cardiac disease has been related to heart dose after left-sided breast radiotherapy. This trial evaluates the heart sparing ability and feasibility of deep inspiration breath… Expand
  • 48
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In vitro cellular radiosensitivity in relationship to late normal tissue reactions in breast cancer patients: a multi-endpoint case-control study
Abstract Purpose: A minority of patients exhibits severe late normal tissue toxicity after radiotherapy (RT), possibly related to their inherent individual radiation sensitivity. This study aimed to… Expand
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Whole breast radiotherapy in prone and supine position: is there a place for multi-beam IMRT?
BackgroundEarly stage breast cancer patients are long-term survivors and finding techniques that may lower acute and late radiotherapy-induced toxicity is crucial. We compared dosimetry of wedged… Expand
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