On the Additive and Dominant Variance and Covariance of Individuals Within the Genomic Selection Scope
- Z. Vitezica, L. Varona, A. Legarra
- BiologyGenetics
- 11 October 2013
A matrix of dominant genomic relationships across individuals, D, is described, similar to the G matrix used in genomic best linear unbiased prediction, which can be used in a mixed-model context for genomic evaluations or to estimate dominant and additive variances in the population.
Orthogonal Estimates of Variances for Additive, Dominance, and Epistatic Effects in Populations
- Z. Vitezica, A. Legarra, M. Toro, L. Varona
- BiologyGenetics
- 18 May 2017
It is proved for the first time that, even not in HWE, the multiple-loci NOIA method is equivalent to construct epistatic genomic relationship matrices for higher-order interactions using Hadamard products of additive and dominant genomic orthogonal relationships.
Analysis of Litter Size and Average Litter Weight in Pigs Using a Recursive Model
- L. Varona, D. Sorensen, Robin Thompson
- Environmental ScienceGenetics
- 1 November 2007
It is shown that there is a one-to-one correspondence between the parameters of SMM and RMM and that they generate equivalent likelihoods, and it is argued that the choice between a SMM or a RMM should be guided by the availability of software, by ease of interpretation, or by the need to test a particular theory or hypothesis.
Bayesian inference of variance components for litter size in Rasa Aragonesa sheep.
- J. Altarriba, L. Varona, L. García-Cortés, C. Moreno
- Biology, MedicineJournal of Animal Science
- 1998
Litter size is a trait that could be selected for in breeding programs and the results indicate that the lack of pedigree information has little effect on the estimates of heritability.
A Bayesian analysis of the effect of selection for growth rate on growth curves in rabbits
As a consequence of selection, the selected animals were heavier than the C animals throughout the entire growth curve, and adult body weight was 7% higher in the selected line than in the control line.
QTL mapping for teat number in an Iberian-by-Meishan pig intercross.
- C. Rodríguez, A. Tomàs, J. Noguera
- Medicine, BiologyAnimal Genetics
- 1 December 2005
The results showed three genomewide significant QTL mapping on chromosomes 5, 10 and 12, whose joint action control up to 30% of the phenotypic variance of the trait.
Fine mapping of porcine chromosome 6 QTL and LEPR effects on body composition in multiple generations of an Iberian by Landrace intercross.
- C. Óvilo, A. Fernández, M. Toro
- Medicine, BiologyGenetical research
- 1 February 2005
The results support the presence of two QTL on SSC6 and support the association between LEPR alleles and BF(T) traits and the possible functional implications of the analysed polymorphisms.
Detection of QTL affecting fatty acid composition in the pig
- A. Clop, C. Óvilo, J. Noguera
- Biology, MedicineMammalian Genome
- 1 September 2003
This is the first report of a genome scan detection of QTL directly affecting fatty acid composition in pigs, and shows how critical the selection of a covariate can be in the interpretation of results.
A note on mate allocation for dominance handling in genomic selection
The objective of this study was to quantify the efficiency of including dominance effects and practising mating allocation under a whole-genome evaluation scenario and, in addition, to improve the expected genetic response over random mating only in the first generation of selection.
Threshold-linear versus linear-linear analysis of birth weight and calving ease using an animal model: II. Comparison of models.
- L. Varona, I. Misztal, J. K. Bertrand
- Medicine, MathematicsJournal of Animal Science
- 1 August 1999
Although the bivariate models for calving ease/birth weight were more accurate than univariate models, the threshold models showed a greater advantage under the b Linear-threshold model, which seems justified for the purpose of genetic evaluation for caling difficulty in beef cattle.
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