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Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii.
This communication describes the consensus multi-locus typing scheme established by the Cryptococcal Working Group I (Genotyping of Cryptococcus neoformans and C. gattii) of the International SocietyExpand
Regional pattern of the molecular types of Cryptococcus neoformans and Cryptococcus gattii in Brazil.
Primary cryptococcosis caused by the molecular type VGII prevails in immunocompetent hosts in the North and Northeast regions, disclosing an endemic regional pattern for this specific molecular type in the Northern Brazil. Expand
Serotyping of 467 Cryptococcus neoformans Isolates from Clinical and Environmental Sources in Brazil: Analysis of Host and Regional Patterns
The epidemiology of serotype A in the Brazilian southern and southeastern regions reproduces the picture observed worldwide, and serotype B was the most frequent agent of cryptococcosis in the northeastern region, occurring nearly equally in male and female healthy hosts. Expand
Geographically Structured Populations of Cryptococcus neoformans Variety grubii in Asia Correlate with HIV Status and Show a Clonal Population Structure
Observations of high gene flow between the Middle Eastern and the Southeastern Asian populations suggest that immigrant workers in the Middle East were originally infected in Southeastern Asia. Expand
Molecular Epidemiology Reveals Genetic Diversity amongst Isolates of the Cryptococcus neoformans/C. gattii Species Complex in Thailand
A greater genetic diversity and a wider range of major molecular types being present amongst Thai cryptococcal isolates than previously reported are revealed. Expand
Cryptococcus neoformans-Cryptococcus gattii Species Complex: an International Study of Wild-Type Susceptibility Endpoint Distributions and Epidemiological Cutoff Values for Fluconazole, Itraconazole,
In the absence of clinical breakpoints, the authors' ECVs may aid in the detection of isolates with acquired resistance mechanisms and should be listed in the revised CLSI M27-A3 and CLSIM27-S3 documents. Expand
In Vitro Antifungal Susceptibility of Cryptococcus gattii
In general, C. gattii was less susceptible than C. neoformans to all drugs tested, with the exception of amphotericin B and flucytosine. Expand
Correlation of antifungal susceptibility and molecular type within the Cryptococcus neoformans/C. gattii species complex.
It is reported that the molecular type VGII is the least susceptible genotype, followed by VGI and VNI, which indicates a clear correlation between antifungal susceptibilities and genotypes of the causative cryptococcosis agents, emphasizing the importance of determining the molecular types as part of the clinical diagnostic process. Expand
Possible primary ecological niche of Cryptococcus neoformans.
C. neoformans and C. gattii were found sharing the same natural biotope, thus establishing a possible link between them in their life cycle in nature and suggesting the primary natural niche for the species. Expand
Natural habitat of Cryptococcus neoformans var. neoformans in decaying wood forming hollows in living trees.
C. neoformans was repeatedly isolated from decaying wood forming hollows in living trees growing in urban areas of Rio de Janeiro, Brazil, finding a new natural habitat for C. neoforms that is not associated with specific trees. Expand