L. Thornton

Publications174
h-index52
Citations11,949
Highly Influential Citations460
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Comorbidity of anxiety disorders with anorexia and bulimia nervosa.
TLDR
The prevalence of anxiety disorders in general and OCD in particular was much higher in people with anorexia nervosa and bulimia nervosa than in a nonclinical group of women in the community.
Analysis of shared heritability in common disorders of the brain
TLDR
It is demonstrated that, in the general population, the personality trait neuroticism is significantly correlated with almost every psychiatric disorder and migraine, and it is shown that both psychiatric and neurological disorders have robust correlations with cognitive and personality measures.
Features associated with excessive exercise in women with eating disorders.
TLDR
Excessive exercise may be associated particularly with the purging subtype of AN as well as with a constellation of anxious/obsessional temperament and personality characteristics among women with eating disorders.
Stressful life events and previous episodes in the etiology of major depression in women: an evaluation of the "kindling" hypothesis.
TLDR
The results are consistent with the kindling hypothesis but suggest a threshold at which the mind/brain is no longer additionally sensitized to the depressive state.
Symptom fluctuation in eating disorders: correlates of diagnostic crossover.
TLDR
The results indicate that personality and family characteristics may influence the course of eating disorders and may be informative for planning interventions.
Genome-wide meta-analyses identify multiple loci associated with smoking behavior
TLDR
A meta-analyses of several smoking phenotypes within cohorts of the Tobacco and Genetics Consortium found the strongest association was a synonymous 15q25 SNP in the nicotinic receptor gene CHRNA3, and three loci associated with number of cigarettes smoked per day were identified.
Genetic risk, number of previous depressive episodes, and stressful life events in predicting onset of major depression.
TLDR
The association between stressful life events and the onset of major depression decreases as the number of previous depressive episodes increases, and genetic risk factors for depression produce a "prekindling" effect rather than increase the speed of kindling.
Gender differences in the rates of exposure to stressful life events and sensitivity to their depressogenic effects.
TLDR
The results suggest that the greater prevalence of major depression in women versus men is due neither to differences in the rates of reported stressful life events nor to differential sensitivity to their pathogenic effect.
Application of a latent class analysis to empirically define eating disorder phenotypes.
TLDR
The presence of obsessive-compulsive features differentiates among individuals with restricting AN and the combination of low weight and multiple methods of purging distinguishes among Individuals with binge eating and purging behaviors.
Personality characteristics of women before and after recovery from an eating disorder
TLDR
Findings suggest that disturbances may be trait-related and contribute to the disorders' pathogenesis, and additional research with more representative community controls, rather than pre-screened, normal controls, is needed to confirm these impressions.
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