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Comorbidity of anxiety disorders with anorexia and bulimia nervosa.
OBJECTIVE A large and well-characterized sample of individuals with anorexia nervosa and bulimia nervosa from the Price Foundation collaborative genetics study was used to determine the frequency ofExpand
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Features associated with excessive exercise in women with eating disorders.
OBJECTIVE Excessive exercise and motor restlessness are observed in a substantial number of patients with eating disorders. This trait has been studied extensively among animal models of activityExpand
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Stressful life events and previous episodes in the etiology of major depression in women: an evaluation of the "kindling" hypothesis.
OBJECTIVE Although previous evidence has suggested that the etiologic role of stressful life events in major depression is reduced in recurrent versus first-onset cases, this question deservesExpand
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Analysis of shared heritability in common disorders of the brain
Brainstorming diseases Consistent classification of neuropsychiatric diseases is problematic because it can lead to misunderstanding of etiology. The Brainstorm Consortium examined multipleExpand
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Symptom fluctuation in eating disorders: correlates of diagnostic crossover.
OBJECTIVE The course of anorexia nervosa often includes the emergence of bulimic symptoms and a crossover to the full syndrome of bulimia nervosa. However, clinicians' ability to predict who willExpand
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Genetic risk, number of previous depressive episodes, and stressful life events in predicting onset of major depression.
OBJECTIVE The association between stressful life events and the onset of major depression decreases as the number of previous depressive episodes increases. How do genetic risk factors for majorExpand
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Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Consistent but indirect evidence has implicated genetic factors in smoking behavior. We report meta-analyses of several smoking phenotypes within cohorts of the Tobacco and Genetics Consortium (n =Expand
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Gender differences in the rates of exposure to stressful life events and sensitivity to their depressogenic effects.
OBJECTIVE Women are at greater risk for major depression than men. The authors sought to determine whether the gender difference in prevalence for major depression was due to more frequent exposureExpand
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Significant Locus and Metabolic Genetic Correlations Revealed in Genome-Wide Association Study of Anorexia Nervosa.
OBJECTIVE The authors conducted a genome-wide association study of anorexia nervosa and calculated genetic correlations with a series of psychiatric, educational, and metabolic phenotypes. METHODExpand
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Sexual orientation in a U.S. national sample of twin and nontwin sibling pairs.
OBJECTIVE Although previous studies have suggested that sexual orientation is influenced by familial factors, which may be partly genetic, these studies have relied on unrepresentative andExpand
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