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- Publications
- Influence
A tutorial on pilot studies: the what, why and how
- L. Thabane, Jinhui Ma, +7 authors C. Goldsmith
- Medicine
- BMC medical research methodology
- 6 January 2010
Pilot studies for phase III trials - which are comparative randomized trials designed to provide preliminary evidence on the clinical efficacy of a drug or intervention - are routinely performed in… Expand
Adherence to antiretroviral therapy in sub-Saharan Africa and North America: a meta-analysis.
- E. Mills, J. Nachega, +10 authors D. Bangsberg
- Medicine
- JAMA
- 9 August 2006
CONTEXT
Adherence to antiretroviral therapy is a powerful predictor of survival for individuals living with human immunodeficiency virus (HIV) and AIDS. Concerns about incomplete adherence among… Expand
Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled…
- M. Meade, D. Cook, +14 authors T. Stewart
- Medicine
- JAMA
- 13 February 2008
CONTEXT
Low-tidal-volume ventilation reduces mortality in critically ill patients with acute lung injury and acute respiratory distress syndrome. Instituting additional strategies to open collapsed… Expand
CONSORT 2010 statement: extension to randomised pilot and feasibility trials
- S. Eldridge, C. Chan, +4 authors G. Lancaster
- Medicine
- British Medical Journal
- 24 October 2016
The Consolidated Standards of Reporting Trials (CONSORT) statement is a guideline designed to improve the transparency and quality of the reporting of randomised controlled trials (RCTs). In this… Expand
Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework
- S. Eldridge, G. Lancaster, +4 authors C. Bond
- Medicine
- PloS one
- 15 March 2016
We describe a framework for defining pilot and feasibility studies focusing on studies conducted in preparation for a randomised controlled trial. To develop the framework, we undertook a Delphi… Expand
Randomized trial of primary PCI with or without routine manual thrombectomy.
- Sanjit S. Jolly, J. Cairns, +30 authors V. Dz̆avík
- Medicine
- The New England journal of medicine
- 8 April 2015
BACKGROUND
During primary percutaneous coronary intervention (PCI), manual thrombectomy may reduce distal embolization and thus improve microvascular perfusion. Small trials have suggested that… Expand
Individualized electronic decision support and reminders to improve diabetes care in the community: COMPETE II randomized trial
- A. Holbrook, L. Thabane, +6 authors H. Gerstein
- Medicine
- Canadian Medical Association Journal
- 7 July 2009
Background: Diabetes mellitus is a complex disease with serious complications. Electronic decision support, providing information that is shared and discussed by both patient and physician,… Expand
Adherence to Antiretroviral Therapy in Sub-Saharan Africa and North America
- E. Mills, J. Nachega, +5 authors L. Thabane
- Medicine
- 2006
Montessori et al,52 2000 0.57 (0.54-0.60) Robertson et al,51 2006 0.68 (0.50-0.82) Temoshok and Wald,5
- 131
- 21
Myocardial Injury after Noncardiac Surgery: A Large, International, Prospective Cohort Study Establishing Diagnostic Criteria, Characteristics, Predictors, and 30-day Outcomes
- F. Botto, P. Alonso-Coello, +264 authors T. Wildes
- Medicine
- Anesthesiology
- 1 March 2014
Background:Myocardial injury after noncardiac surgery (MINS) was defined as prognostically relevant myocardial injury due to ischemia that occurs during or within 30 days after noncardiac surgery.… Expand
Systematic review of long-term weight loss studies in obese adults: clinical significance and applicability to clinical practice
- J. Douketis, C. Macie, L. Thabane, D. Williamson
- Medicine
- International Journal of Obesity
- 1 October 2005
BACKGROUND:Obesity is a common health problem that requires a long-term care approach. We systematically reviewed long-term (≥2 y) studies investigating dietary/lifestyle, pharmacologic, and surgical… Expand