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Metabolic effects of fructose and the worldwide increase in obesity.
While virtually absent in our diet a few hundred years ago, fructose has now become a major constituent of our modern diet. Our main sources of fructose are sucrose from beet or cane, high fructoseExpand
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Regulation of body weight in humans.
The mechanisms involved in body weight regulation in humans include genetic, physiological, and behavioral factors. Stability of body weight and body composition requires that energy intake matchesExpand
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Fructose and metabolic diseases: new findings, new questions.
There has been much concern regarding the role of dietary fructose in the development of metabolic diseases. This concern arises from the continuous increase in fructose (and total added caloricExpand
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Differential effects of hyperinsulinemia and carbohydrate metabolism on sympathetic nerve activity and muscle blood flow in humans.
Euglycemic hyperinsulinemia evokes both sympathetic activation and vasodilation in skeletal muscle, but the mechanism remains unknown. To determine whether insulin per se or insulin-inducedExpand
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Impaired insulin-induced sympathetic neural activation and vasodilation in skeletal muscle in obese humans.
The sympathetic nervous system is an important regulatory mechanism of both metabolic and cardiovascular function, and altered sympathetic activity may play a role in the etiology and/orExpand
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Effect of fructose overfeeding and fish oil administration on hepatic de novo lipogenesis and insulin sensitivity in healthy men.
High-fructose diet stimulates hepatic de novo lipogenesis (DNL) and causes hypertriglyceridemia and insulin resistance in rodents. Fructose-induced insulin resistance may be secondary to alterationsExpand
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Metabolic effects of fructose
Purpose of reviewFructose is consumed in significant amounts in Western diets. An increase in fructose consumption over the past 10–20 years has been linked with a rise in obesity and metabolicExpand
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Effect of a Thermogenic Beverage on 24‐Hour Energy Metabolism in Humans
Objective: To test whether consumption of a beverage containing active ingredients will increase 24‐hour energy metabolism in healthy, young, lean individuals.
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A 4-wk high-fructose diet alters lipid metabolism without affecting insulin sensitivity or ectopic lipids in healthy humans.
BACKGROUND High fructose consumption is suspected to be causally linked to the epidemics of obesity and metabolic disorders. In rodents, fructose leads to insulin resistance and ectopic lipidExpand
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Effects of Breakfast Cereals Containing Various Amounts of β-Glucan Fibers on Plasma Glucose and Insulin Responses in NIDDM Subjects
OBJECTIVE To determine whether increasing doses (amounts) of β-glucan present in an extruded breakfast cereal affect the glycemic and insulinemic responses in eight NIDDM subjects, compared with theExpand
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