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Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a
TLDR
It is concluded that patients with CLL can break immune tolerance to ROR1, which is an oncofetal surface antigen and survival-signaling receptor in this neoplastic disease. Expand
Splat Feature Classification With Application to Retinal Hemorrhage Detection in Fundus Images
TLDR
A novel splat feature classification method is presented with application to retinal hemorrhage detection in fundus images, and has potential to be applied to other object detection tasks. Expand
Rice zinc finger protein DST enhances grain production through controlling Gn1a/OsCKX2 expression
TLDR
DSTreg1, a semidominant allele of the DST gene, perturbs DST-directed regulation of OsCKX2 expression and elevates CK levels in the reproductive SAM, leading to increased meristem activity, enhanced panicle branching, and a consequent increase of grain number. Expand
Investigating the optimal size of anticancer nanomedicine
TLDR
Among the three NCs investigated, the 50-nm NC shows the highest tumor tissue retention integrated over time, which is the collective outcome of deep tumor tissue penetration and efficient cancer cell internalization as well as slow tumor clearance, and thus, the highest efficacy against both primary and metastatic tumors in vivo. Expand
Nonporous Silica Nanoparticles for Nanomedicine Application.
TLDR
The current state of the development and application of nonporous silica NPs for drug delivery and molecular imaging is reviewed. Expand
Robust Multiscale Stereo Matching from Fundus Images with Radiometric Differences
TLDR
A robust multiscale stereo matching algorithm is proposed to find reliable correspondences between low contrast and weakly textured retinal image pairs with radiometric differences to obtain globally coherent reconstructions. Expand
Structural brain abnormalities in patients with primary open-angle glaucoma: a study with 3T MR imaging.
TLDR
Three-dimensional MRI revealed widespread abnormalities in the central nervous system beyond the visual cortex in patients with advanced primary open-angle glaucoma. Expand
Automated 3-D method for the correction of axial artifacts in spectral-domain optical coherence tomography images
TLDR
A novel technique that uses thin-plate splines in two stages to estimate and correct the distinct axial artifacts in SD-OCT images and is quantitatively validated using nine pairs of OCT scans obtained with orthogonal fast-scanning axes. Expand
Morphological characterization of the immune organs in ostrich chicks
TLDR
The data indicate that the immune organs of ostrich chicks, especially the spleen and cloacal bursa, have numerous distinct, conformational, and structural features. Expand
Biomaterial Strategies for Immunomodulation.
TLDR
Recent advances in the field of biomaterials for immunomodulation are reviewed, focusing particularly on designing biommaterials to provide controlled immunostimulation, targeting drugs and vaccines to lymphoid organs, and serving as scaffolds to organize immune cells and emulate lymphoid tissues. Expand
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