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PlantTFDB 2.0: update and improvement of the comprehensive plant transcription factor database
We updated the plant transcription factor (TF) database to version 2.0, http://planttfdb.cbi.edu.cn) which contains 53 319 putative TFs predicted from 49 species. Expand
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The Structure of an Infectious P22 Virion Shows the Signal for Headful DNA Packaging
Bacteriophages, herpesviruses, and other large double-stranded DNA (dsDNA) viruses contain molecular machines that pump DNA into preassembled procapsids, generating internal capsid pressuresExpand
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The structure of a thermophilic archaeal virus shows a double-stranded DNA viral capsid type that spans all domains of life.
Of the three domains of life (Eukarya, Bacteria, and Archaea), the least understood is Archaea and its associated viruses. Many Archaea are extremophiles, with species that are capable of growth atExpand
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Structure of an archaeal virus capsid protein reveals a common ancestry to eukaryotic and bacterial viruses.
Archaea and their viruses are poorly understood when compared with the Eukarya and Bacteria domains of life. We report here the crystal structure of the major capsid protein (MCP) of the SulfolobusExpand
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Wnt/beta-catenin signaling contributes to activation of normal and tumorigenic liver progenitor cells.
Adult hepatic progenitor (oval) cells are facultative stem cells in liver, which participate in a range of human liver diseases, including hepatocellular carcinoma (HCC). However, the molecularExpand
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The structure of Pariacoto virus reveals a dodecahedral cage of duplex RNA
The 3.0 Å resolution crystal structure of Pariacoto virus (PaV) reveals extensive interactions between portions of the viral RNA genome and the icosahedral capsid. Under the protein shell of the T =Expand
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Profound impact of gut homeostasis on chemically-induced pro-tumorigenic inflammation and hepatocarcinogenesis in rats.
BACKGROUND & AIMS Due to its anatomic connection, the liver is constantly exposed to gut-derived bacterial products or metabolites. Disruption of gut homeostasis is associated with many humanExpand
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Prognostic Significance of AMPK Activation and Therapeutic Effects of Metformin in Hepatocellular Carcinoma
Purpose: The AMP-activated protein kinase (AMPK) serves as an energy sensor in eukaryotic cells and occupies a central role in linking metabolism and cancer development. However, the phosphorylationExpand
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Uncertainties in predicting rice yield by current crop models under a wide range of climatic conditions.
Predicting rice (Oryza sativa) productivity under future climates is important for global food security. Ecophysiological crop models in combination with climate model outputs are commonly used inExpand
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Structures of the phage Sf6 large terminase provide new insights into DNA translocation and cleavage
Many DNA viruses use powerful molecular motors to cleave concatemeric viral DNA into genome-length units and package them into preformed procapsid powered by ATP hydrolysis. Here we report theExpand
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