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Pharmacodynamic effects and pharmacokinetic profile of a long-term continuous rate infusion of racemic ketamine in healthy conscious horses.
TLDR
It was concluded that a KET CRI of 1.5 mg/kg/h can safely be administered to healthy conscious horses for at least 6 h, although a slight modification of the initial infusion rate regimen may be indicated. Expand
Textbook of Veterinary Anesthesia
EIPH: postrace endoscopic evaluation of Standardbreds and Thoroughbreds.
TLDR
There was no apparent effect of breed (or possibly racing gait) on EIPH, and no differences in the incidence or severity of EipH were observed between horses with or without prerace frusemide administration. Expand
Sudden death attributable to exercise-induced pulmonary hemorrhage in racehorses: nine cases (1981-1983).
TLDR
Underlying respiratory tract lesions, particularly those associated with small airway disease or bronchiolitis, may have a role in fatal pulmonary hemorrhage. Expand
Equine leukocyte antigens: Relationships with sarcoid tumors and laminitis in two pure breeds
TLDR
Findings suggest that a strong relationship exists between the equine MHC and a predisposition to sarcoid, as well as between antigenic expression frequencies and laminitis in either breed. Expand
Pharmacokinetics of dexamethasone following intra-articular, intravenous, intramuscular, and oral administration in horses and its effects on endogenous hydrocortisone.
TLDR
The pharmacokinetic estimates for intra-articular (IA) administration of dexamethasone sodium phosphate into three equine joints, femoropatellar (IAS), radiocarpal (IAC), and metacarpophalangeal (IAF), and the intramuscular (IM), oral (PO) and intravenous (IV) administrations were compared. Expand
Endoscopic findings in the upper respiratory tract of 678 Thoroughbred racehorses.
TLDR
The frequency of upper respiratory tract abnormalities was determined in a selected population of racing Thoroughbreds in order to determine the prevalence of pharyngeal lymphoid hyperplasia and tracheal exudate. Expand
Pharmacokinetics of fentanyl administered transdermally and intravenously in sheep.
TLDR
Investigation of the pharmacokinetics of fentanyl administered transdermally and IV in sheep resulted in a short half-life and application of a TFP resulted in stable blood fentanyl concentrations in sheep. Expand
Effects of furosemide on the racing times of Thoroughbreds.
TLDR
Furosemide failed to prevent the development of EIPH in many horses that were previously considered to be EIPh-negative, and had questionable efficacy for prevention of EipH in known E IPH-positive horses. Expand
Pharmacokinetics of amikacin in the horse following intravenous and intramuscular administration.
TLDR
Based on the MIC and the pharmacokinetic parameters, it would appear that the usual therapeutic dose of amikacin would be between 4.4 and 6.6 mg/kg twice daily and, for the more serious life-threatening infections, dosing three times a day. Expand
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