L. Sinoway

Publications303
h-index53
Citations8,410
Highly Influential Citations350
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Influences of gender on sympathetic nerve responses to static exercise.
We compared reflex responses to static handgrip at 30% maximal voluntary contraction (MVC) in 26 untrained men (mean age 35 +/- 3 yr) and 23 untrained women (mean age 39 +/- 4 yr). Women demonstrated… Expand
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Gender affects sympathetic and hemodynamic response to postural stress.
We tested the hypothesis that differences in sympathetic reflex responses to head-up tilt (HUT) between males (n = 9) and females (n = 8) were associated with decrements in postural vasomotor… Expand
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ATP concentrations and muscle tension increase linearly with muscle contraction.
Previous studies have suggested that activation of ATP-sensitive P2X receptors in skeletal muscle play a role in mediating the exercise pressor reflex (Li J and Sinoway LI. Am J Physiol Heart Circ… Expand
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Muscle Mechanoreflex and Metaboreflex Responses After Myocardial Infarction in Rats
Background—During exercise, the sympathetic nervous system is activated and blood pressure and heart rate increase. In heart failure (HF), the muscle metaboreceptor contribution to sympathetic… Expand
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Enhanced maximal metabolic vasodilatation in the dominant forearms of tennis players.
In an effort to evaluate potential peripheral adaptations to training, maximal metabolic vasodilation was studied in the dominant and nondominant forearms of six tennis players and six control… Expand
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ATP stimulates chemically sensitive and sensitizes mechanically sensitive afferents.
  • J. Li, L. Sinoway
  • Chemistry, Medicine
  • American journal of physiology. Heart and…
  • 1 December 2002
We examined whether ATP stimulation of P2X purinoceptors would raise blood pressure in decerebrate cats. Femoral arterial injection of the P2X receptor agonist alpha,beta-methylene ATP into the blood… Expand
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Effects of the ovarian cycle on sympathetic neural outflow during static exercise.
We compared reflex responses to static handgrip at 30% maximal voluntary contraction (MVC) in 10 women (mean age 24.1 +/- 1.7 yr) during two phases of their ovarian cycle: the menstrual phase (days… Expand
  • 106
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Muscle sympathetic nerve activity responses to dynamic passive muscle stretch in humans
It is suggested that mechanoreceptors in muscle play an important role in the exercise pressor reflex. However, it has not been verified whether isolated stimulation of the mechanoreceptors can… Expand
  • 94
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Surges of muscle sympathetic nerve activity during obstructive apnea are linked to hypoxemia.
Obstructive sleep apnea (OSA) is associated with oscillations of arterial blood pressure (BP) that occur in phase with irregularities of respiration. To explore the role of the sympathetic nervous… Expand
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Aging and the Exercise Pressor Reflex in Humans
Background—Blood flow limitation to exercising muscles engages the muscle reflex during exercise, evoking an increase in heart rate (HR), blood pressure (BP), and muscle sympathetic nerve activity… Expand
  • 56
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