L. Singh

Publications269
h-index54
Citations12,750
Highly Influential Citations798
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Reconstructing Indian Population History
TLDR
It is predicted that there will be an excess of recessive diseases in India, which should be possible to screen and map genetically and is higher in traditionally upper caste and Indo-European speakers.
The Simons Genome Diversity Project: 300 genomes from 142 diverse populations
TLDR
It is demonstrated that indigenous Australians, New Guineans and Andamanese do not derive substantial ancestry from an early dispersal of modern humans; instead, their modern human ancestry is consistent with coming from the same source as that of other non-Africans.
Ancient human genomes suggest three ancestral populations for present-day Europeans
TLDR
It is shown that the great majority of present-day Europeans derive from at least three highly differentiated populations: West European Hunter-Gatherers (WHG), who contributed ancestry to all Europeans but not to Near Easterners; Ancient North Eurasians (ANE); and Early European Farmers (EEF), who were mainly of Near Eastern origin but also harbored WHG-related ancestry.
Identification, characterization and utilization of EST-derived genic microsatellite markers for genome analyses of coffee and related species
TLDR
The study provides an insight about the frequency and distribution of SSRs in coffee transcriptome, and also demonstrates the successful development of genic-SSRs.
Genome-wide analysis of microsatellite repeats in humans: their abundance and density in specific genomic regions
TLDR
The overall SSR density was comparable in all chromosomes, but the density of different repeats, however, showed significant variation.
Reconstructing the Origin of Andaman Islanders
TLDR
Analysis of complete mitochondrial DNA sequences from Onges and Great Andaman populations revealed two deeply branching clades that share their most recent common ancestor in founder haplogroup M, with lineages spread among India, Africa, East Asia, New Guinea, and Australia.
Missense mutations in the BMP15 gene are associated with ovarian failure
TLDR
The haplotype G-G-C was found to be significantly associated with ovarian failure (P=0.0075), and the BMP15 gene is highly associated with etiology of ovarian failure.
Genetic evidence for recent population mixture in India.
Most Indian groups descend from a mixture of two genetically divergent populations: Ancestral North Indians (ANI) related to Central Asians, Middle Easterners, Caucasians, and Europeans; and…
Phylogeography and origin of Indian domestic goats.
TLDR
The present investigation of 363 goats belonging to 10 different breeds from different geographic regions of India using mtDNA sequence data from the HVRI region finds evidence for population structure and novel lineages in Indian goats and proposes a more complex origin for domestic goats.
Genetic Affinities of the Andaman Islanders, a Vanishing Human Population
TLDR
The data indicate that the Andamanese have closer affinities to Asian than to African populations and suggest that they are the descendants of the early Palaeolithic colonizers of Southeast Asia.
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