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Xenobiotic metabolizing enzyme activities in rat, mouse, monkey, and human testes.
- K. DiBiasio, M. Silva, L. Shull, J. Overstreet, B. Hammock, M. Miller
- Biology, MedicineDrug metabolism and disposition: the biological…
Comparing enzyme activities in subcellular fractions prepared from rat, mouse, monkey, and human testes indicates that species differences in capacity to metabolize xenobiotics may play a role in differential sensitivity to testicular toxicants.
Effect of technical grade pentachlorophenol on rumen microorganisms.
The results suggest that technical grade pentachlorophenol has the potential to interfere with utilization of cellulose in ruminants.
Eggshell thinning in ring doves exposed top,p′-dicofol
Analysis of covariance revealed a statistically significant effect of decreasing eggshell thickness over time in doves fed DDE and dic ofol diets but not in control birds, and egg production was significantly lower in both dicofol-fed and DDE-fed birds when compared with controls.
Subchronic administration of technical pentachlorophenol to lactating dairy cattle: immunotoxicologic evaluation.
- J. Forsell, L. Shull, J. Kateley
- Chemistry, MedicineJournal of toxicology and environmental health
- 1 October 1981
The results showed no statistically significant differences between control and pent-treated cattle during eigher treatment period, and no histopathologic changes were noted in lymphoid tissues including spleen, thymus, and lymph node.
A technique for isolation of bovine hepatocytes.
The potential usefulness of isolated bovine hepatocytes in xenobiotic metabolism studies is illustrated by the epoxidation of aldrin.
Interlobular distribution of hepatic xenobiotic-metabolizing enzyme activities in cattle, goats and sheep.
Microsomal and cytosolic enzymes that metabolize xenobiotics were measured in composite samples representing entire livers and in samples from three lobes, using livers of cattle, goats and sheep, with cattle livers generally having lower values than sheep or goats.
Comparative Toxicology of Tetrachlorobiphenyls in Mink and Rats I. Changes in Hepatic Enzyme Activity and Smooth Endoplasmic Reticulum Volume
Abstract Mink have been shown previously to be extraordinarily sensitive to polychlorinated biphenyls (PCBs) and related classes of halogenated hydrocarbons. This study explored several aspects of…
Polychlorinated biphenyls (Aroclors® 1016 and 1242): Effect on hepatic microsomal mixed function oxidases in mink and ferrets
- L. Shull, M. Bleavins, B. Olson, R. Aulerich
- Biology, MedicineArchives of environmental contamination and…
An inverse relationship between extent of MC-type induction and toxicity in mink and European ferrets is suggested, and greater induction was noted in ferrets compared to mink.