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Automatically parcellating the human cerebral cortex.
A technique for automatically assigning a neuroanatomical label to each location on a cortical surface model based on probabilistic information estimated from a manually labeled training set is presented, comparable in accuracy to manual labeling.
Biological Insights From 108 Schizophrenia-Associated Genetic Loci
Associations at DRD2 and several genes involved in glutamatergic neurotransmission highlight molecules of known and potential therapeutic relevance to schizophrenia, and are consistent with leading pathophysiological hypotheses.
The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validity.
- K. Nuechterlein, Michael F. Green, S. Marder
- Psychology, MedicineThe American journal of psychiatry
- 1 February 2008
The MATRICS Consensus Cognitive Battery is expected to be the standard tool for assessing cognitive change in clinical trials of cognition-enhancing drugs for schizophrenia and may also aid evaluation of cognitive remediation strategies.
Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia
- S. Whitfield-Gabrieli, H. Thermenos, L. Seidman
- Psychology, MedicineProceedings of the National Academy of Sciences
- 27 January 2009
Among patients, the magnitude of MPFC task suppression negatively correlated with default connectivity, suggesting an association between the hyperactivation and hyperconnectivity in schizophrenia.
Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America.
These findings demonstrate that prospective ascertainment of individuals at risk for psychosis is feasible, with a level of predictive accuracy comparable to that in other areas of preventive medicine.
Distinct genetic influences on cortical surface area and cortical thickness.
It is demonstrated that cortical volume measures combine at least 2 distinct sources of genetic influences, and using volume in a genetically informative study, or as an endophenotype for a disorder, may confound the underlying genetic architecture of brain structure.
Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging.
A permutation test showed that, compared to other brain areas assessed in this study, there was greater sexual dimorphism among brain areas that are homologous with those identified in animal studies showing greater levels of sex steroid receptors during critical periods of brain development.
Impact of executive function deficits and attention-deficit/hyperactivity disorder (ADHD) on academic outcomes in children.
- J. Biederman, M. Monuteaux, S. Faraone
- Psychology, MedicineJournal of consulting and clinical psychology
- 1 October 2004
The association between executive function deficits (EFDs) and functional outcomes were examined among children and adolescents with attention-deficit/hyperactivity disorder (ADHD) and these results support screening children with ADHD for EFDs to prevent academic failure.
Anterior cingulate cortex dysfunction in attention-deficit/hyperactivity disorder revealed by fMRI and the counting stroop
The psychosis high-risk state: a comprehensive state-of-the-art review.
The relatively new field of HR research in psychosis has the potential to shed light on the development of major psychotic disorders and to alter their course and provides a rationale for service provision to those in need of help who could not previously access it.