L. Seethalakshmi

Publications37
h-index15
Citations794
Highly Influential Citations17
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Effect of cyclosporine A on male reproduction in rats.
We examined the effects of the immunosuppressive drug cyclosporine A on male reproduction in sexually mature rats. The drug was administered subcutaneously in 3 doses (10, 20 and 40 mg. per kg.… Expand
  • 74
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Neurotensin receptor expression in prostate cancer cell line and growth effect of NT at physiological concentrations
Neurotensin (NT), a neuroendocrine peptide, exerts trophic effects in vivo and stimulates growth of some tumor cells in vitro. Androgen‐sensitive prostate cells derived from lymph node carcinoma of… Expand
  • 93
  • 2
The effect of streptozotocin-induced diabetes on the neuroendocrine-male reproductive tract axis of the adult rat.
Studies in the streptozotocin rat model for diabetes mellitus suggest that sexual dysfunction in these animals may result from diabetes-induced alterations of the neuroendocrine-reproductive tract… Expand
  • 146
  • 2
Effects of vitamin C deficiency on physiology of male reproductive organs of guinea pigs.
Vitamin C dietary deficiency in guinea pigs markedly affected the androgen-sensitive parameters of the reproductive tissues--testis, epididymis, vas deferens, and accessory sex glands--and caused an… Expand
  • 51
  • 2
Effects of sialoadenectomy and epidermal growth factor on testicular function of sexually mature male mice.
The effect of sialoadenectomy (Sx) and epidermal growth factor (EGF) administration on testicular function was investigated in 8-week old C3H mice. Animals were divided initially into three groups:… Expand
  • 46
  • 2
Effects of subchronic treatment with cis-platinum on testicular function, fertility, pregnancy outcome, and progeny.
Cis-platinum-based chemotherapy is known to impair spermatogenesis, but the effects of paternal cis-platinum treatment on the progeny are unknown. To study this effect, sexually mature male… Expand
  • 36
  • 2
Quantitative maintenance of spermatogenesis in cyclosporine-treated rats by exogenous administration of testosterone propionate.
The authors had previously shown that the subcutaneous administration of cyclosporine (CsA) resulted in an impairment of spermatogenesis. Testosterone levels declined and gonadotropin levels… Expand
  • 18
  • 2
Short term effects of cis-platinum on male reproduction, fertility and pregnancy outcome.
In order to find out the short term effects of cis-platinum treatment on reproductive function of the treated male rats and their progeny, sexually mature male Sprague-Dawley rats were given a single… Expand
  • 24
  • 1
The effects of an LHRH agonist on testicular function in the cryptorchid rat.
To assess the effects of an LHRH analog (LHRH-ethylamide des gly10 D-Leu6) on the function of the cryptorchid testis, an animal model was created, using prepubertal male Sprague-Dawley rats (21 days… Expand
  • 13
  • 1
Effect of cryptorchidism and orchidopexy on inhibin secretion by rat Sertoli cells.
The present study explored the effects of experimental bilateral cryptorchidism (of 21-, 28-, and 35-days duration) and orchidopexy (14 and 42 days) in the adult rat on the secretion of inhibin by… Expand
  • 19