• Publications
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Graves Ophthalmopathy: The Bony Orbit in Optic Neuropathy, Its Apical Angular Capacity, and Impact on Prediction of Risk
TLDR
Orbital wall angles, especially the medial wall, and muscular enlargement are independent risk predictors of Optic neuropathy. Expand
Ethnic differences in the clinical presentation of Graves' ophthalmopathy.
TLDR
There is some evidence to suggest Asian patients with GO may manifest milder phenotypic features of GO, with less proptosis and evidence of extraocular muscle involvement and restriction. Expand
The combination of absent thyroid peroxidase antibodies and high thyroid-stimulating immunoglobulin levels in Graves' disease identifies a group at markedly increased risk of ophthalmopathy.
  • D. Khoo, S. Ho, +6 authors A. Fok
  • Medicine
  • Thyroid : official journal of the American…
  • 1 December 1999
TLDR
The combination of negative TPOAb and high TSI levels appears to be associated with a markedly increased risk of clinically evident ophthalmopathy. Expand
Thyroid autoantibody profiles in ophthalmic dominant and thyroid dominant Graves’ disease differ and suggest ophthalmopathy is a multiantigenic disease
TLDR
Thyroid‐associated ophthalmopathy occurs in 25–50% of patients with Graves’ disease and is occasionally seen in hypothyroid Hashimoto's disease or euthyroid individuals, and qualitative or quantitative differences in thyroid antibodies might determine individual predisposition to these features. Expand
Orbital Cellulitis in Children—Medical Treatment Versus Surgical Management
TLDR
Paediatric orbital cellulitis can be treated conservatively or with surgical drainage and Sole medical treatment worked well in children with no orbital abscess, small or medial abscesses as they tend to have a single organism infection. Expand
A Novel Bioresorbable Implant for Repair of Orbital Floor Fractures
TLDR
This bioresorbable implant is a promising material for the repair of both small and large orbital floor fractures, giving good functional and aesthetic outcomes. Expand
Nasopharyngeal Carcinoma With Orbital Involvement
TLDR
Ocular symptoms and signs may be the initial presentation of recurrent nasopharyngeal carcinoma and orbital involvement and one must be aware of possible tumor recurrence in patients with a prior history of nasoph throat carcinoma who present with symptoms of tearing or an eyelid mass to enable prompt referral to the oncologist and otorhinolaryngologist. Expand
An Unusual Causative Agent for an Orbital Abscess: Granulicatella Adiacens
TLDR
This is the first reported case of a posttraumatic orbital abscess associated with Granulicatella Adiacens, a nutritionally variant streptococcus, and this is a multidisciplinary approach with input from the ophthalmologist, microbiologist and infectious disease team. Expand
Graves' ophthalmopathy in the absence of elevated free thyroxine and triiodothyronine levels: prevalence, natural history, and thyrotropin receptor antibody levels.
  • D. Khoo, P. Eng, +7 authors S. Aw
  • Medicine
  • Thyroid : official journal of the American…
  • 1 December 2000
TLDR
The high prevalence of thyrotropin receptor antibodies (TRAb) in Graves' ophthalmopathy cases supports a role for these antibodies in the pathogenesis of thyroid-associated eye disease. Expand
Congenital Upper Lid Colobomas: Management and Visual Outcome
TLDR
Close monitoring of the visual development of patients with congenital upper eyelid colobomas is also essential since the risk of amblyopia in these patients is high. Expand
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