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Analyses of pig genomes provide insight into porcine demography and evolution
TLDR
The assembly and analysis of the genome sequence of a female domestic Duroc pig and a comparison with the genomes of wild and domestic pigs from Europe and Asia reveal a deep phylogenetic split between European and Asian wild boars ∼1 million years ago. Expand
Design of a High Density SNP Genotyping Assay in the Pig Using SNPs Identified and Characterized by Next Generation Sequencing Technology
TLDR
The results of this study indicate the utility of using next generation sequencing technologies to identify large numbers of reliable SNPs and demonstrate that the PorcineSNP60 Beadchip is an excellent tool that will likely be used in a variety of future studies in pigs. Expand
Dynamics of Mammalian Chromosome Evolution Inferred from Multispecies Comparative Maps
TLDR
It is found that segmental duplications populate the majority of primate-specific breakpoints and often flank inverted chromosome segments, implicating their role in chromosomal rearrangement. Expand
A first-generation porcine whole-genome radiation hybrid map
TLDR
This initial radiation map of the porcine genome forms a template for establishing accurate YAC and BAC contigs and eventual positional cloning of genes associated with complex traits. Expand
Construction of a whole-genome radiation hybrid panel for high-resolution gene mapping in pigs
TLDR
The initial results for this chromosome indicate that the resolution of the radiation hybrid map is 18 times higher than that obtained by linkage analysis. Expand
A high density recombination map of the pig reveals a correlation between sex-specific recombination and GC content
TLDR
The analysis of the recombination rate along the pig genome highlighted that the regions exhibiting higher levels of recombination tend to cluster around the ends of the chromosomes irrespective of the location of the centromere. Expand
Genome sequencing reveals fine scale diversification and reticulation history during speciation in Sus
TLDR
This case study demonstrates that genomics is a powerful tool to decipher the evolutionary history of a genus, and reveals the complexity of the process of speciation in island Southeast Asia, by sequencing and analyzing the genomes of 10 wild pigs. Expand
Piggy-BACing the human genome II. A high-resolution, physically anchored, comparative map of the porcine autosomes.
TLDR
A human-pig comparative map composed of 2274 loci, including 206 ESTs and 2068 BAC-end sequences, assigned to 34 linkage groups that will greatly facilitate the positional cloning of genes influencing complex traits of both agricultural and biomedical interest. Expand
Regions of Homozygosity in the Porcine Genome: Consequence of Demography and the Recombination Landscape
TLDR
An in-depth study of genomic variation based on three different parameters: nucleotide diversity outside ROHs, the number of R OHs in the genome, and the average ROH size, which shows an unequal genomic ROH distribution. Expand
Genome-Wide Footprints of Pig Domestication and Selection Revealed through Massive Parallel Sequencing of Pooled DNA
TLDR
Although domesticated breeds have experienced similar selective pressures, selection has acted upon different genes that might reflect the multiple domestication events of European breeds or could be the result of subsequent introgression of Asian alleles. Expand
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