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Genomics, transcriptomics, and peptidomics of Daphnia pulex neuropeptides and protein hormones.
We report 43 novel genes in the water flea Daphnia pulex encoding 73 predicted neuropeptide and protein hormones as partly confirmed by RT-PCR. MALDI-TOF mass spectrometry identified 40 neuropeptides
Insights into social insects from the genome of the honeybee Apis mellifera
The genome sequence of the honeybee Apis mellifera is reported, suggesting a novel African origin for the species A. melliferA and insights into whether Africanized bees spread throughout the New World via hybridization or displacement.
UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans
Uncoordinated movement in Rab2 mutants is caused by impaired retention of cargo on dense core vesicles, not by defective synaptic vesicle release. (Also see the companion article by Edwards et al. in
Genomics, transcriptomics, and peptidomics of neuropeptides and protein hormones in the red flour beetle Tribolium castaneum.
The authors' analysis of Tribolium indicates that, during insect evolution, genes for neuropeptides and protein hormones are often duplicated or lost.
From the Genome to the Proteome: Uncovering Peptides in the Apis Brain
This study lays the groundwork for future molecular studies of Apis neuropeptides with the identification of 36 genes, 33 of which were previously unreported, and inferred more than 200 peptides within the Apis mellifera genome.
Identification of the gregarization-associated dark-pigmentotropin in locusts through an albino mutant.
Results show that even in isolated (solitary) nymphs, [His7] corazonin induces gregarious black patterns, and its primary structure shows some similarity with the vertebrate melanophore stimulating hormone.
Characterization of an orphan G protein-coupled receptor localized in the dorsal root ganglia reveals adenine as a signaling molecule
It is demonstrated that adenine functions as a signaling molecule in mammals and adds a third family besides P1 and P2 receptors to the class of purinergic receptors.