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Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure.
In patients with advanced heart failure and a prolonged QRS interval, cardiac-resynchronization therapy decreases the combined risk of death from any cause or first hospitalization and, when combined with an implantable defibrillator, significantly reduces mortality. Expand
Cardiac resynchronization therapy for the treatment of heart failure in patients with intraventricular conduction delay and malignant ventricular tachyarrhythmias.
The CRT improved functional status in patients indicated for an ICD who also have symptomatic HF and intraventricular conduction delay and a subgroup of patients with advanced HF consistently demonstrated improvement across all functional status end points. Expand
Identification of Reentry Circuit Sites During Catheter Mapping and Radiofrequency Ablation of Ventricular Tachycardia Late After Myocardial Infarction
Criteria for identifying reentry circuit sites using computer simulations was developed and tested during catheter mapping in humans to predict sites at which radiofequency current application terminated ventricular tachycardia. Expand
Cardiac resynchronization therapy and the relationship of percent biventricular pacing to symptoms and survival.
Every effort should be made to reduce native atrioventricular conduction with cardiac resynchronization therapy systems in an attempt to achieve biventricular pacing as close to 100% as possible. Expand
Radiofrequency catheter ablation of ventricular tachycardia after myocardial infarction.
Radiofrequency catheter ablation controls VT that is sufficiently stable to allow mapping in 67% of patients despite failure of antiarrhythmic drug therapy and multiple inducible VTs. Expand
Ventricular contraction abnormalities in dilated cardiomyopathy: effect of biventricular pacing to correct interventricular dyssynchrony.
Improvements in interventricular synchrony during biventricular pacing correlate with acute improvements in LV ejection fraction, and Dilated cardiomyopathy with intraventricular conduction delay is associated with significant intervent cardiac dyssynchrony. Expand
Long-Term Outcome After ICD and CRT Implantation and Influence of Remote Device Follow-Up: The ALTITUDE Survival Study
Remote follow-up of device data is associated with excellent survival, but arrhythmias that result in device therapy in this population are associated with a higher mortality risk compared with patients who do not require shock therapy. Expand
Activation and entrainment mapping defines the tricuspid annulus as the anterior barrier in typical atrial flutter.
Closely spaced sites around the tricuspid annulus are activated sequentially, and are all within the flutter circuit according to entrainment criteria, demonstrating that the trICuspidannulus constitutes a continuous anterior barrier constraining the reentrant wave front of human counterclockwise atrial flutter. Expand
Heart failure management using implantable devices for ventricular resynchronization: Comparison of Medical Therapy, Pacing, and Defibrillation in Chronic Heart Failure (COMPANION) trial. COMPANION
The COMPANION study is a randomized, open-label, 3-arm study of patients in New York Heart Association class III or IV with an ejection fraction of 35% or less and a QRS duration of 120 milliseconds or less to determine whether optimal pharmacological therapy used with ventricular resynchronization therapy alone or with cardioverter-defibrillator capability is superior to optimal Pharmacological therapy alone in reducing combined all-cause mortality and hospitalizations. Expand
2012 EHRA/HRS expert consensus statement on cardiac resynchronization therapy in heart failure: implant and follow-up recommendations and management.
1 S 2012 EHRA/HRS expert consensus statement on cardiac resynchronization therapy in heart failure: implant and follow-up recommendations and management Developed in partnership with the EuropeanExpand