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Novel DNA assay for cytomegalovirus detection: comparison with conventional culture and pp65 antigenemia assay
TLDR
The pp65 antigenemia assay is a rapid and reliable method of detecting CMV and is preferable to culture, but the Murex HCS appears to be more sensitive for CMV detection.
Inhibitory effects of IFN-gamma on HIV-1 replication in latently infected cells.
TLDR
It is found that IFN-gamma induces CIITA through the JAK-STAT pathway and inhibits HIV-1 replication in latently infected cells and can be considered as an adjunct to the currently available therapy.
RelA-Associated Inhibitor Blocks Transcription of Human Immunodeficiency Virus Type 1 by Inhibiting NF-κB and Sp1 Actions
TLDR
RAI acts as an efficient inhibitor of HIV-1 gene expression in which both NF-κB and Sp1 play major roles, and is efficiently blocked when cotransfected with a full-length HIV- 1 clone.
Inhibitory effects of IFN-γ on HIV-1 replication in latently infected cells
TLDR
It is found that IFN-gamma induces CIITA through the JAK-STAT pathway and inhibits HIV-1 replication in latently infected cells and can be considered as an adjunct to the currently available therapy.
Human cytomegalovirus DNA kinetics using a novel HCMV DNA quantitative assay in white blood cells of immunocompromised patients under Ganciclovir therapy.
TLDR
HCMV DNA quantitation in WBC appears well adapted for a therapeutic follow up of patients with HCMV disease, and two-fold higher clearances and initial DNA levels were observed in the AIDS group compared to the transplant group.
In vitro Inhibition Kinetics of Crocodylus mindorensis (Philippine crocodile) Serum against Human Immunodeficiency Virus Type I Reverse Transcriptase
TLDR
The inhibition kinetics of the Philippine crocodile suggests a potential novel HIV-1 Reverse Transcriptase inhibitor.