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Nitazoxanide: a new thiazolide antiparasitic agent.
TLDR
Nitazoxanide is a new thiazolide antiparasitic agent that shows excellent in vitro activity against a wide variety of protozoa and helminths and is well tolerated, with primarily mild gastrointestinal side effects. Expand
Methicillin-resistant Staphylococcus aureus. Epidemiologic observations during a community-acquired outbreak.
TLDR
Infection with strains of methicillin-resistant Staphylococcus aureus occurred in 40 patients at time of admission to a large urban hospital from March to December 1980 and has the potential to disseminate in both settings. Expand
Ceftaroline: a novel cephalosporin with activity against methicillin-resistant Staphylococcus aureus.
TLDR
Ceftaroline is consistently active against multidrug-resistant Streptococcus pneumoniae and Staphylococcus aureus, including methicillin-resistant, vancomycin-intermediate, linezolid- resistant, and daptomycin-nonsusceptible strains. Expand
Community-acquired methicillin-resistant Staphylococcus aureus infections: a new source for nosocomial outbreaks.
Over a 19-month period, 165 patients with 183 infections caused by community-acquired, methicillin-resistant Staphylococcus aureus were seen at Henry Ford Hospital in Detroit, Michigan. TheExpand
Effect Of Nurse-Led Multidisciplinary Rounds On Reducing the Unnecessary Use Of Urinary Catheterization in Hospitalized Patients
TLDR
A nurse-led multidisciplinary approach to evaluate the need for UCs was associated with a reduction of unnecessary UC use and efforts to sustain the intervention-induced reduction may be successful when trained advocates continue this effort with each team. Expand
Gatifloxacin, gemifloxacin, and moxifloxacin: the role of 3 newer fluoroquinolones.
TLDR
These agents can be useful for treatment of bacterial respiratory tract infections in patients who are allergic to beta-lactams, but caution must be exercised to avoid the potential for selection of widespread resistance, which may occur with indiscriminate use. Expand
Epidemiology and clinical outcomes of infective endocarditis in hemodialysis patients.
TLDR
The prognosis of infective endocarditis in hemodialysis patients is poor, with surgery serving as an independent predictor of survival, and valve surgery was the only independent factor predicting survival on logistic regression. Expand
Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO.
TLDR
Because of its safety record and multiple novel mechanisms of action, minocycline may be a valuable cardioprotective agent to ameliorate cardiac dysfunction and cell loss associated with cardiac I/R injury. Expand
Broad-range bacterial polymerase chain reaction for early detection of bacterial meningitis.
TLDR
Broad-range bacterial PCR may be useful for excluding the diagnosis of meningitis, and the results may influence the decision to initiate or discontinue antimicrobial therapy. Expand
Trimethoprim-sulfamethoxazole compared with vancomycin for the treatment of Staphylococcus aureus infection.
TLDR
Vancomycin is superior to TMP-SMZ in efficacy and safety when treating intravenous drug users who have staphylococcal infections, however, all treatment failures occurred in patients with MSSA infection at any site. Expand
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