• Publications
  • Influence
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system
TLDR
It is shown that regulatory components of the venom secretory system may have evolved from a pancreatic origin and that venom toxin genes were co-opted by distinct genomic mechanisms, which provides insight into mechanisms of protein evolution under strong selection. Expand
Snake venomics of the lancehead pitviper Bothrops asper: geographic, individual, and ontogenetic variations.
TLDR
This study represents the first detailed characterization of individual and ontogenetic venom protein profile variations in two geographical isolated B. asper populations, and highlights the necessity of using pooled venoms as a statistically representative venom for antivenom production. Expand
Venoms, venomics, antivenomics
TLDR
Proteomic protocols for uncoiling the composition, immunological profile, and evolution of snake venoms are reviewed to gain a deep insight of all viperid venom proteomes. Expand
Seminal Plasma Proteins: What Role Do They Play?
Citation Rodríguez‐Martínez H, Kvist U, Ernerudh J, Sanz L, Calvete JJ. Seminal Plasma Proteins: What Role Do They Play? Am J Reprod Immunol 2011; 66 (Suppl. 1): 11–22
Snake venomics of the Central American rattlesnake Crotalus simus and the South American Crotalus durissus complex points to neurotoxicity as an adaptive paedomorphic trend along Crotalus dispersal
TLDR
The increased concentration of the neurotoxins crotoxin and crotamine in South American rattlesnake venoms strongly argues that the gain of neurotoxicity and lethal venom activities to mammals may have represented the key axis along which overall venom toxicity has evolved during Crotalus durissus invasion of South America. Expand
Venom variability and envenoming severity outcomes of the Crotalus scutulatus scutulatus (Mojave rattlesnake) from Southern Arizona.
TLDR
Health severity outcomes between two Arizona counties U.S.A., Pima and Cochise, were determined by retrospective chart review of the Arizona Poison and Drug Information Center (APDIC) database between the years of 2002 and 2009 by identifying venom protein families based on six phenotypes. Expand
Snake venom disintegrins: evolution of structure and function.
TLDR
The role of the composition, conformation, and dynamics of the integrin inhibitory loop acting in concert with the C-terminal tail in determining the selective inhibition of integrin receptors is discussed. Expand
Snake venomics and antivenomics of Crotalus durissus subspecies from Brazil: assessment of geographic variation and its implication on snakebite management.
TLDR
The results revealed that both antivenoms exhibit impaired immunoreactivity towards crotamine and display restricted recognition of PLA(2) molecules from C. durissus subspecies populations, supporting the view that these taxa can be considered geographical variations of the same species. Expand
Cryosurvival and in vitro fertilizing capacity postthaw is improved when boar spermatozoa are frozen in the presence of seminal plasma from good freezer boars.
TLDR
The addition of SP from good sperm freezers improved the motility and viability of thawed spermatozoa without any influence on MDA production and increased the percentage of penetrated (SP3) and polyspermic oocytes (SP4) with respect to the control. Expand
Spermadhesins: A new protein family. Facts, hypotheses and perspectives
TLDR
Spermadhesins are a novel family of secretory proteins expressed in the male genital tract of pig, horse and bull and have been found to be peripherally associated to the sperm surface, suggesting that they may be involved in different steps of fertilization. Expand
...
1
2
3
4
5
...