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Snake venomics of the lancehead pitviper Bothrops asper: geographic, individual, and ontogenetic variations.
- A. Alape-Girón, L. Sanz, J. Calvete
- Biology, Environmental ScienceJournal of proteome research
- 17 June 2008
This study represents the first detailed characterization of individual and ontogenetic venom protein profile variations in two geographical isolated B. asper populations, and highlights the necessity of using pooled venoms as a statistically representative venom for antivenom production.
The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system
- F. Vonk, N. Casewell, M. Richardson
- BiologyProceedings of the National Academy of Sciences
- 2 December 2013
It is shown that regulatory components of the venom secretory system may have evolved from a pancreatic origin and that venom toxin genes were co-opted by distinct genomic mechanisms, which provides insight into mechanisms of protein evolution under strong selection.
Seminal Plasma Proteins: What Role Do They Play?
- H. Rodríguez-Martínez, U. Kvist, J. Ernerudh, L. Sanz, J. Calvete
- BiologyAmerican journal of reproductive immunology
- 1 July 2011
Citation Rodríguez‐Martínez H, Kvist U, Ernerudh J, Sanz L, Calvete JJ. Seminal Plasma Proteins: What Role Do They Play? Am J Reprod Immunol 2011; 66 (Suppl. 1): 11–22
Venoms, venomics, antivenomics
Snake venomics of the Central American rattlesnake Crotalus simus and the South American Crotalus durissus complex points to neurotoxicity as an adaptive paedomorphic trend along Crotalus dispersal…
The increased concentration of the neurotoxins crotoxin and crotamine in South American rattlesnake venoms strongly argues that the gain of neurotoxicity and lethal venom activities to mammals may have represented the key axis along which overall venom toxicity has evolved during Crotalus durissus invasion of South America.
Snake venom disintegrins: evolution of structure and function.
Snake venomics. Strategy and applications.
- J. Calvete, Paula Juárez, L. Sanz
- Biology, ChemistryJournal of mass spectrometry : JMS
- 1 November 2007
The combined strategy allows us to assign unambiguously all the isolated venom toxins representing over 0.05% of the total venom proteins to known protein families.
Snake venomics and antivenomics of Crotalus durissus subspecies from Brazil: assessment of geographic variation and its implication on snakebite management.
Snake venomics and antivenomics of Bothrops atrox venoms from Colombia and the Amazon regions of Brazil, Perú and Ecuador suggest the occurrence of geographic variation of venom phenotype by a trend…
Cryosurvival and in vitro fertilizing capacity postthaw is improved when boar spermatozoa are frozen in the presence of seminal plasma from good freezer boars.
The addition of SP from good sperm freezers improved the motility and viability of thawed spermatozoa without any influence on MDA production and increased the percentage of penetrated (SP3) and polyspermic oocytes (SP4) with respect to the control.