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- Publications
- Influence
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
- D. Klionsky, Kotb Abdelmohsen, +2,464 authors S. Zughaier
- Biology, Medicine
- Autophagy
- 18 April 2012
In 2008 we published the first set of guidelines for
standardizing research in autophagy. Since then, research on
this topic has continued to accelerate, and many new scientists
have entered the… Expand
Microautophagy of cytosolic proteins by late endosomes.
- R. Sahu, S. Kaushik, +7 authors L. Santambrogio
- Biology, Medicine
- Developmental cell
- 18 January 2011
Autophagy delivers cytosolic components to lysosomes for their degradation. The delivery of autophagic cargo to late endosomes for complete or partial degradation has also been described. In this… Expand
Molecular definitions of autophagy and related processes
- L. Galluzzi, E. Baehrecke, +51 authors G. Kroemer
- Biology, Medicine
- The EMBO journal
- 3 July 2017
Over the past two decades, the molecular machinery that underlies autophagic responses has been characterized with ever increasing precision in multiple model organisms. Moreover, it has become clear… Expand
Proteomic Analysis of Microglia-Derived Exosomes: Metabolic Role of the Aminopeptidase CD13 in Neuropeptide Catabolism1
- Ilaria Potolicchio, G. J. Carven, +4 authors L. Santambrogio
- Biology, Medicine
- The Journal of Immunology
- 15 August 2005
Vesicle transport is a fundamental mechanism of communication in the CNS. In this study we characterized a novel type of vesicle released by murine brain microglial cells: microglial exosomes.… Expand
Oxidative stress, inflamm-aging and immunosenescence.
- Elvira S. Cannizzo, Cristina C. Clement, R. Sahu, Carlo Follo, L. Santambrogio
- Biology, Medicine
- Journal of proteomics
- 19 October 2011
Immunosenescence is characterized by a decreased ability of the immune system to respond to foreign antigens, as well as a decreased ability to maintain tolerance to self-antigens. This results in an… Expand
Nerve growth factor production by lymphocytes.
- L. Santambrogio, M. Benedetti, +4 authors G. Hochwald
- Biology, Medicine
- Journal of immunology
- 15 November 1994
Nerve growth factor (NGF) is a neurotrophic protein essential for the maintenance and growth of peripheral sympathetic neurons and basal forebrain cholinergic neurons. Recently, NGF has also been… Expand
Molecular analysis of chromium and cobalt-related toxicity
- Brian Scharf, Cristina C. Clement, +9 authors L. Santambrogio
- Chemistry, Medicine
- Scientific reports
- 17 July 2014
Occupational and environmental exposure to Co and Cr has been previously linked to a wide array of inflammatory and degenerative conditions and cancer. Recently, significant health concerns have been… Expand
Short communication: Methamphetamine treatment increases in vitro and in vivo HIV replication.
- S. Toussi, A. Joseph, J. Zheng, Monica Dutta, L. Santambrogio, H. Goldstein
- Biology, Medicine
- AIDS research and human retroviruses
- 1 November 2009
To delineate the mechanistic basis for the epidemiological association between methamphetamine use and accelerated progression to AIDS, we evaluated the direct in vitro and in vivo effects of… Expand
Methamphetamine Inhibits Antigen Processing, Presentation, and Phagocytosis
- Z. Tallóczy, J. Martínez, +9 authors L. Santambrogio
- Biology, Medicine
- PLoS pathogens
- 1 February 2008
Methamphetamine (Meth) is abused by over 35 million people worldwide. Chronic Meth abuse may be particularly devastating in individuals who engage in unprotected sex with multiple partners because it… Expand
Intralymphatic CCL21 Promotes Tissue Egress of Dendritic Cells through Afferent Lymphatic Vessels.
- Erica Russo, A. Teijeira, +7 authors C. Halin
- Biology, Medicine
- Cell reports
- 23 February 2016
To induce adaptive immunity, dendritic cells (DCs) migrate through afferent lymphatic vessels (LVs) to draining lymph nodes (dLNs). This process occurs in several consecutive steps. Upon entry into… Expand