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- Publications
- Influence
Progress in the development of selective nitric oxide synthase (NOS) inhibitors.
- L. Salerno, V. Sorrenti, C. Di Giacomo, G. Romeo, M. A. Siracusa
- Chemistry, Medicine
- Current pharmaceutical design
- 31 January 2002
Nitric oxide (NO), a molecular messenger synthesized by nitric oxide synthase (NOS) from L-arginine and molecular oxygen, is involved in a number of physiological and pathological processes in… Expand
Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries.
- E. Amata, V. Pittalà, +5 authors L. Salerno
- Medicine
- Clinical science
- 15 July 2017
Bronchopulmonary dysplasia (BPD) is a chronic illness that usually originates in preterm newborns. Generally, BPD is a consequence of respiratory distress syndrome (RDS) which, in turn, comes from… Expand
Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole derivatives as potent and selective 5-HT1A serotonin receptor ligands.
- M. A. Siracusa, L. Salerno, +8 authors T. Mennini
- Chemistry, Medicine
- Journal of medicinal chemistry
- 4 July 2008
A series of new compounds containing a benzimidazole, benzothiazole, or benzoxazole nucleus linked to an arylpiperazine by different thioalkyl chains was prepared. They were tested in radioligand… Expand
A focus on heme oxygenase-1 (HO-1) inhibitors.
- V. Pittalà, L. Salerno, G. Romeo, M. Modica, M. A. Siracusa
- Chemistry, Medicine
- Current medicinal chemistry
- 30 September 2013
The aim of this review is to highlight the advances in the field of heme oxygenase-1 (HO-1) inhibitors over the past years, particularly from a medicinal chemistry point of view; progresses made in… Expand
Heme oxygenase-1: A new druggable target in the management of chronic and acute myeloid leukemia.
- L. Salerno, G. Romeo, +4 authors V. Pittalà
- Medicine
- European journal of medicinal chemistry
- 20 July 2017
Heme oxygenase-1 (HO-1) is the enzyme catalyzing the rate-limiting oxidative degradation of cellular heme into free iron, carbon monoxide (CO), and biliverdin, which is then rapidly converted into… Expand
Simultaneous determination of catechins, rutin, and gallic acid in Cistus species extracts by HPLC with diode array detection.
- N. A. Santagati, L. Salerno, G. Attaguile, F. Savoca, G. Ronsisvalle
- Chemistry, Medicine
- Journal of chromatographic science
- 1 February 2008
A simple high-performance liquid chromatography method using a diode array detector (DAD) is developed for the simultaneous analysis of five major catechins: (+)-catechin (C), (-)-epicatechin (EC),… Expand
[1,2,4]Triazole derivatives as 5-HT(1A) serotonin receptor ligands.
- M. Sarva, G. Romeo, +6 authors T. Mennini
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 1 February 2002
A series of new 4-amino-3-[3-[4-(2-methoxy or nitro phenyl)-1-piperazinyl] propyl]thio]-5-(substitutedphenyl)[1,2,4]triazoles 11a-t was synthesized in order to obtain compounds with high affinity and… Expand
Antioxidant Activity and Phenolic Content of Microwave-Assisted Solanum melongena Extracts
- L. Salerno, M. Modica, +5 authors R. Acquaviva
- Medicine, Chemistry
- TheScientificWorldJournal
- 9 February 2014
Eggplant fruit is a very rich source of polyphenol compounds endowed with antioxidant properties. The aim of this study was to extract polyphenols from eggplant entire fruit, pulp, or skin, both… Expand
Inhibition of Human Leucocyte Elastase by Novel Thieno-1,3-oxazin-4-ones and Thieno-1,3-thioxazin-4-ones
- N. A. Santagati, L. Salerno, C. Giacomo, L. Vanella, Simone Ronsisvalle
- Chemistry
- 31 August 2007
Evaluation of novel aryloxyalkyl derivatives of imidazole and 1,2,4-triazole as heme oxygenase-1 (HO-1) inhibitors and their antitumor properties.
- L. Salerno, V. Pittalà, +7 authors V. Sorrenti
- Chemistry, Medicine
- Bioorganic & medicinal chemistry
- 1 September 2013
A novel series of aryloxyalkyl derivatives of imidazole and 1,2,4-triazole, 17-31, was designed and synthesized as inhibitors of heme oxygenase-1 (HO-1) and heme oxygenase-2 (HO-2). Some of these… Expand
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