• Publications
  • Influence
The use of mosquitoes to detect and propagate dengue viruses.
  • L. Rosen, D. Gubler
  • Biology, Medicine
  • The American journal of tropical medicine and…
  • 1 November 1974
Abstract Parenteral inoculation of Aedes albopictus mosquitoes was found to be a much more sensitive method to detect dengue viruses than was plaque assay in LLC-MK2 cells—the most sensitive dengueExpand
  • 393
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Horizontal and vertical transmission of Japanese encephalitis virus by Aedes japonicus (Diptera: Culicidae).
Aedes japonicus (Theobald) was evaluated for competence as a vector of Japanese encephalitis virus and for its ability to transmit the virus vertically to its F1 larvae. Ae. japonicus supported theExpand
  • 95
  • 13
The Emperor's New Clothes revisited, or reflections on the pathogenesis of dengue hemorrhagic fever.
  • L. Rosen
  • Medicine
  • The American journal of tropical medicine and…
  • 1 May 1977
As most of you know, one of the duties of the President of the American Society of Tropical Medicine and Hygiene specified by the by-laws is the presentation of an address at the annual meet ing. IExpand
  • 251
  • 10
  • PDF
Life history of the canine lungworm Angiostrongylus vasorum (Baillet).
  • 124
  • 10
Epidemiologic, clinical, and virologic observations on dengue in the Kingdom of Tonga.
An outbreak of dengue type 2 infection occurred in the Pacific island Kingdom of Tonga in 1974 and an outbreak of dengue type 1 occurred there in 1975. The 1974 outbreak was characterized byExpand
  • 190
  • 8
The natural history of Japanese encephalitis virus.
  • L. Rosen
  • Biology, Medicine
  • Annual review of microbiology
  • 1986
  • 186
  • 8
A hemagglutination-inhibition technique for typing adenoviruses.
  • L. Rosen
  • Medicine
  • American journal of hygiene
  • 1960
  • 224
  • 7
Molecular epidemiology of dengue-1 and dengue-4 viruses.
Genetic variation between geographically and temporally distinct isolates of dengue-1 (DEN-1) and dengue-4 (DEN-4) viruses was investigated. The nucleotide sequences of a fragment of the envelopeExpand
  • 109
  • 7
Growth-restricted dengue virus mutants containing deletions in the 5' noncoding region of the RNA genome.
The dengue type 4 virus (DEN4) RNA genome contains a 101-nt 5' noncoding (NC) sequence which is predicted to form a stable secondary structure. DEN4 cDNA from which infectious RNA can be transcribedExpand
  • 133
  • 6
Transovarial transmission of dengue viruses by mosquitoes: Aedes albopictus and Aedes aegypti.
Transovarial transmission of all four dengue serotypes was demonstrated in Aedes albopictus mosquitoes. The rates of such transmission varied with the serotype and strain of virus. In general, theExpand
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