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- Publications
- Influence
Hypoxia inducible factor-1α induces chemoresistance phenotype in non-Hodgkin lymphoma cell line via up-regulation of Bcl-xL
- M. Hernández-Luna, L. Rocha-Zavaleta, M. Vega, S. Huerta-Yepez
- Biology, Medicine
- Leukemia & lymphoma
- 1 May 2013
Abstract Non-Hodgkin lymphoma (NHL) is one of the most common cancers in childhood. The development of chemoresistance in tumor cells is one of the principal causes of treatment failure. This… Expand
Autocrine/paracrine erythropoietin signalling promotes JAK/STAT‐dependent proliferation of human cervical cancer cells
- T. Lopez, T. Lappin, +4 authors L. Rocha-Zavaleta
- Medicine
- International journal of cancer
- 1 December 2011
Erythropoietin (Epo) regulates erythropoiesis by binding to its receptor (EpoR) and promoting cell proliferation, differentiation and inhibition of apoptosis. Epo is widely used to treat cervical… Expand
Prevalence of human papillomavirus genotypes, and mucosal IgA anti-viral responses in women with cervical ectopy.
- Olga L. Monroy, C. Aguilar, M. Lizano, F. Cruz-Talonia, Rosa M Cruz, L. Rocha-Zavaleta
- Biology, Medicine
- Journal of clinical virology : the official…
- 2010
BACKGROUND
Data on the prevalence of different human papillomavirus (HPV) genotypes and the associated mucosal immune response in women with cervical ectopy are scarce.
OBJECTIVE
To assess the… Expand
The role of signaling pathways in cervical cancer and molecular therapeutic targets.
- Joaquín Manzo-Merino, A. Contreras-Paredes, Elenaé Vázquez-Ulloa, L. Rocha-Zavaleta, A. M. Fuentes-González, M. Lizano
- Medicine
- Archives of medical research
- 1 October 2014
Cervical cancer is a public health issue in developing countries. Although the Pap smear and colposcopy remain the major strategies for detection, most cases are diagnosed in the late stages.… Expand
IL-2 Enhances Cervical Cancer Cells Proliferation and JAK3/STAT5 Phosphorylation at Low Doses, While at High Doses IL-2 Has Opposite Effects
- Arturo Valle-Mendiola, B. Weiss-Steider, L. Rocha-Zavaleta, I. Soto-Cruz
- Biology, Medicine
- Cancer investigation
- 1 April 2014
The IL-2R signaling is critical for normal lymphocyte proliferation. However, the role of the IL-2 signaling in cervical cancer is not yet fully understood. We show that in IL-2R-expressing cervical… Expand
Implication of tyrosine kinase receptor and steel factor in cell density-dependent growth in cervical cancers and leukemias.
- J. R. Cáceres-Cortés, J. A. Alvarado-Moreno, +9 authors T. Hoang
- Biology, Medicine
- Cancer research
- 15 August 2001
Cell-cell interaction is important in the expansion of leukemic cells and of solid tumors. Steel factor (SF) or Kit ligand is produced as a membrane-bound form (mSF) and a soluble form. Because both… Expand
Parenteral and oral immunization with a plasmid DNA expressing the human papillomavirus 16‐L1 gene induces systemic and mucosal antibodies and cytotoxic T lymphocyte responses
- L. Rocha-Zavaleta, Jorge E Alejandre, A. García-Carrancá
- Biology, Medicine
- Journal of medical virology
- 1 January 2002
The association of human papillomavirus (HPV) infection and cervical cancer has been demonstrated. The development of a prophylactic vaccine to protect against primary HPV infection may therefore be… Expand
Human papillomavirus infection and cervical ectopy
- L. Rocha-Zavaleta, G. Yescas, René Méndez Cruz, F. Cruz-Talonia
- Medicine
- International journal of gynaecology and…
- 1 June 2004
Objectives: To investigate the prevalence of human papillomavirus (HPV), and HPV type 16 (HPV16) infection in cervical ectopy, and the presence of anti‐HPV16 secretory IgA (sIgA) antibodies. Methods:… Expand
Benzo[a]pyrene activates an AhR/Src/ERK axis that contributes to CYP1A1 induction and stable DNA adducts formation in lung cells.
- G. Vázquez-Gómez, L. Rocha-Zavaleta, M. Rodríguez-Sosa, P. Petrosyan, J. Rubio-Lightbourn
- Chemistry, Medicine
- Toxicology letters
- 1 June 2018
Benzo[a]pyrene (B[a]P), the most extensively studied carcinogen in cigarette smoke, has been regarded as a critical mediator of lung cancer. It is known that B[a]P-mediated Aryl hydrocarbon Receptor… Expand
Erythropoietin, Stem Cell Factor, and Cancer Cell Migration.
- M. J. Vázquez-Mellado, Victor Monjaras-Embriz, L. Rocha-Zavaleta
- Biology, Medicine
- Vitamins and hormones
- 2017
Cell migration of normal cells is tightly regulated. However, tumor cells are exposed to a modified microenvironment that promotes cell migration. Invasive migration of tumor cells is stimulated by… Expand