• Publications
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Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster.
The decapentaplegic (dpp) gene of Drosophila melanogaster encodes a growth factor that belongs to the transforming growth factor-beta (TGF-beta) superfamily and that plays a central role in multipleExpand
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An extensive 3' cis-regulatory region directs the imaginal disk expression of decapentaplegic, a member of the TGF-beta family in Drosophila.
The decapentaplegic (dpp) gene in Drosophila melanogaster encodes a TGF-beta-like signalling molecule that is expressed in a complex and changing pattern during development. One of dpp'sExpand
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The Drosophila activin receptor baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development.
The TGF-beta superfamily of growth and differentiation factors, including TGF-beta, Activins and bone morphogenetic proteins (BMPs) play critical roles in regulating the development of manyExpand
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Drosophila follicle cells: morphogenesis in an eggshell.
Epithelial morphogenesis is important for organogenesis and pivotal for carcinogenesis, but mechanisms that control it are poorly understood. The Drosophila follicular epithelium is a geneticallyExpand
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Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila.
Pathways for regulation of signaling by transforming growth factor-beta family members are poorly understood at present. The best genetically characterized member of this family is encoded by theExpand
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Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells
  • L. Dobens, L. Raftery
  • Biology, Medicine
  • Developmental dynamics : an official publication…
  • 1 May 2000
Drosophila oogenesis involves the coordinated development of germ cells and an overlying follicular epithelium. The follicle cells provide a genetically tractable system to investigate the cellExpand
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Medea is a Drosophila Smad4 homolog that is differentially required to potentiate DPP responses.
Mothers against dpp (Mad) mediates Decapentaplegic (DPP) signaling throughout Drosophila development. Here we demonstrate that Medea encodes a MAD-related protein that functions in DPP signaling.Expand
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TGF-beta family signal transduction in Drosophila development: from Mad to Smads.
The transforming growth factor-beta (TGF-beta) superfamily encompasses a large group of soluble extracellular proteins that are potent regulators of development in both vertebrates and invertebrates.Expand
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TGF-beta family signal transduction in Drosophila development: from Mad to Smads.
The transforming growth factor-beta (TGF-beta) superfamily encompasses a large group of soluble extracellular proteins that are potent regulators of development in both vertebrates and invertebrates.Expand
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Stepwise formation of a SMAD activity gradient during dorsal-ventral patterning of the Drosophila embryo
Genetic evidence suggests that the Drosophila ectoderm is patterned by a spatial gradient of bone morphogenetic protein (BMP). Here we compare patterns of two related cellular responses, bothExpand
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