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Warfarin inhibition of vitamin K 2,3-epoxide reductase in rat liver microsomes.
Warfarin is a potent inhibitor of vitamin K 2,3-epoxide reduction to vitamin K in vitro and in vivo. Dithiothreitol, an in vitro reductant for the vitamin K 2,3-epoxide reductase, antagonizesExpand
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The End of Alchemy?
The general abandonment of serious endeavor toward metallic transmutation represents a major development in the history of chemistry, yet its exact causes and timing remain unclear. This essayExpand
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The Scientific Revolution: A Very Short Introduction
Introduction: science and natural philosophy 1. New worlds and old worlds 2. The connected world 3. The superlunar world 4. The sublunar world 5. The microcosm and the living world 6. The artificialExpand
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Origins of 1,2- and 1,3-Stereoselectivity in Dicobaltoctacarbonyl Alkene-alkyne Cyclizations for the Synthesis of Substituted Bicyclo[3.3.0]octenones.
Abstract A working mechanistic hypothesis is proposed which rationalizes the stereochemical outcome of the synthesis of substituted bicyclo[3.3.O]octenones, using dicobaltoctacarbonyl mediatedExpand
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Alchemy vs. chemistry: the etymological origins of a historiographic mistake.
The parallel usage of the two terms "alchemy" and "chemistry" by seventeenth-century writers has engendered considerable confusion among historians of science. Many historians have succumbed to theExpand
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Alchemy tried in the fire : Starkey, Boyle, and the fate of Helmontian chemistry
Using the previously misunderstood interactions between Robert Boyle, widely known as "the father of chemistry," and George Starkey, an alchemist and the most prominent American scientific writerExpand
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The Secrets of Alchemy
Alchemy, the "Noble Art," conjures up scenes of mysterious, dimly lit laboratories populated with bearded old men stirring cauldrons. Though the history of alchemy is intricately linked to theExpand
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