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Differentiation of the Cardiovascular Effects of CI‐581
TLDR
The following work, using three different dose levels of ketamine, was carried out to study cardiovascular parameters, and to gain some insight into the nature of these responses. Expand
Sympathetic regulation of the cerebral circulation by the carotid chemoreceptor reflex.
TLDR
In the conscious dog, stimulation of the carotid chemoreceptor reflex elicits significant sympathetically mediated vasoconstriction in cerebral vessels. Expand
The Effect of Beta‐Adrenergic Blockade on the Cardiopulmonary Response to Ketamine
TLDR
It was concluded that the residual pressor response produced by the anesthetic agent after muscarinic blockade must be mediated via the sympathetic nervous system. Expand
Blockade of the Hypertensive Response to Ketamine
TLDR
It is established that ketamine, a sociative anesthetic agent, produces a hypertensive response that may have some therapeutic advantages in some clinical situations, but may also have deleterious effects under some clinical conditions, such as hypertension. Expand
Barbiturate anesthesia: an abnormal physiologic stimulation.
TLDR
It is felt that careful consideration must be given to the choice of agent, if an anesthetic is to be employed in cardiovascular experimentation, and even more preferable would be the use of unanesthetized animals. Expand
Effects of Two New Dissociative Anesthetic Agents, Ketamine and CL‐1848C, on the Respiratory Response to Carbon Dioxide
TLDR
The term “dissociative anesthesia” was used to describe the anesthetic state characteristic of both drugs, and ketamine acts rapidly, on intravenous or intramuscular administration, to produce a state characterized by catalepsy, analgesia, and amnesia. Expand
Morphine Effects on Cardiac Output and Regional Blood Flow Distribution in Conscious Dogs
TLDR
It is concluded that morphine has only minimal effects on systemic hemodynamics, but has significant effects when the alterations it produces in regional hemodynamics are considered. Expand
Effect of Halothane on Renal Hemodynamics during Normovolemia and Acute Hemorrhagic Hypovolemia
TLDR
The author concludes that a moderate degree of acute hemorrhagic hypovolemia does not decrease renal blood flow in conscious dogs and administration of halothane to acutely Hypovolemic conscious dogs does not impair renal perfusion. Expand
Tympanic Thermography: A clinical and Research Evaluation of a New Technic
TLDR
A new method of continuously recording the body temperature in burn patients by use of a thermister probe placed against the ear drum is described. Expand
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